19 - Thyroid Flashcards

1
Q

what hormones are secreted by the Thyroid gland?

A

Thyroxine and Triiodotyronin

t4 and t3

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2
Q

What secretes calcitonin

A

the C-cells of the thyroid gland

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3
Q

Iodine deficiency cause defficits in

A

T4

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4
Q

Through what system does thyroid hormone transport idodes ?

A

NIS - Na+ Iodide symporter

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5
Q

How are thyorid hormones formed

A

Using E.R and Golgi .. who secrete Thyroglobullin - which will combine the iodines from diet to tyrosine.. 1 thyroglobullin has like 70 tyrosine molecules

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6
Q

What is organofication

A

Oxidizing iodine in tyorsine using Peroxidases

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7
Q

How are T.H activated?

A

Through nuclear trnascription, forming a RXR

Higher affinity for T3, so T4 are - 1 iodided to T3

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8
Q

Non Genomic T.H

A
  • Regulation of ion channels
    and
    -Oxid phosphorylation
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9
Q

High and Low level of thyroid hormone on [ ] of fat

A

High level = dec [ ] cholest / phospholipid / TAG

but Inc F. FA

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