23. diffuse large B-cell lymphoma Flashcards
1
Q
what is the treatment for primary mediastinal diffuse large B-cell lymphoma?
A
radiation therapy following R-CHOP
2
Q
What is the cytogenic abnormality of germinal center B-cell DLBCL?
A
overexpression of the BCL-2 gene
translocation leading to rearrangement of the MYC gene
3
Q
What is the cytogenic abnormality of activated B-cell DLBCL?
A
translocation involving the BCL-6 gene
mutation involving the P53 gene
