2.2 The Synthesis and Transport of Proteins iv The Secretory Pathway Flashcards
1
Q
Where are secreted proteins translated?
A
On ribosomes on the RER
2
Q
Once secreted proteins are translated where do they go?
A
They enter the lumen of the RER
3
Q
Two examples of secreted proteins
A
Digestive enzymes and peptide hormones
4
Q
How are proteins secreted from a cell?
A
The proteins move through the Golgi apparatus and are then packaged into secretory vesicles.
These vesicles move to and fuse with the plasma membrane, releasing the proteins out of the cell
5
Q
How do the proteins that have been synthesised as inactive precursors become active proteins?
A
Proteolytic cleavage
6
Q
What is proteolytic cleavage?
A
A type of post- translational modification
7
Q
Example of a protein that requires proteolytic cleavage to become active
A
Digestive enzymes
