22 - SSTI Flashcards
- *CELLULITIS**
- NON-Purulent ABSSSI*
Risk Higher in who?
Poor Blood Flow
DIABETES / OBESITY
Venous Stasis / Lymphedema
Trauma / Surgery
PREVIOUS cellulitis
What type of ABSSI?
- *DEEPER DERMIS** + SUBQ FAT
- not into fascia or muscle*
Most commonly affects = LOWER LEGS
RAPID SPREADING
areas ofErythema/swelling/tenderness/warmth
- *Vesicles / Bullae / Petechiae / Ecchymosis**
- may develop*
RARE SYSTEMIC ISSUES
- *CELLULITIS**
- NON-purulent ABSSI*
Primarily caused by:
STREPtococcus Spp** - **B-HEMOLYTIC Group A
(S. Pyogenes)
B C F G
rarely Staph. Aureus
Treatment:
ABx Therapy
What type of ABSSI?
- *Necrotizing Fasciitis** of the:
- *GENITALS**
Risk Factors:
Older Age 50-60
DIABETES / OBESITY
PeriANAL –> spreads along fascial planes –> Genitalia
- *FOURNIER’S GANGRENE**
- NON-purulent ABSSI*
POLYMICROBIAL
S. Pyogenes / S. Aureus
Aeromonas Hydrophila / Vibrio Vulnificus
What type of ABSSI?
Infection of the:
Hair Follicles
- *Superficial inflammation of Epidermis**
- different from folliculitis*
- *FURUNCLES = Boils**
- *Purulent ABSSSI**
Primarily caused by:
STAPH Aureus
Treatment:
Often ruptures/drain spontaneously w/ moist heat
- *NECROTIZING FASCIITIS**
- NON-Purulent ABSSSI*
CAUSED BY WHAT ORGANISM(s)?
POLYMICROBIAL
Strep. Pyogenes (GAS) / Staph. Aureus (MRSA)
Gram Negatives
Anaerobes
Aeromonas Hydrophila / Vibrio Vulnificus
TREATMENT FOR:
- *SEVERE / MODERATE PURULENT ABSSSI**
- *Cutaneous / Furuncle / Carbuncle**
SYSTEMICALLY ILL
Elevated HR / RR / TEMP / WBC
IMMUNOCOMPROMISED
Multiple Abscesses - Extreme Age
Lack of RESPONSE to I&D
INCISION & DRAINAGE
+
EMPIRIC ABx –> MRSA
Vancomycin / Daptomycin / Linezolid / Doxy / Bactrim
+
Check Cultures –> DEFINED Rx
MSSA Possible –> Nafcillin / Cefazolin / Clindamycin
- *Erysipelas & Cellulitis**
- NON-purulent ABSSSI*
CAUSED BY WHAT ORGANISM(s)?
Primarily caused by:
STREPtococcus SPP.
B-HEMOLYTIC GROUP A
(S. Pyogenes)
Groups: B-C-F-G
rarely Staph Aureus
- *CUTANEOUS ABSCESS**
- *Purulent ABSSSI**
CAUSED BY WHAT ORGANISM(s)?
Painful - Tender - Fluctuant Red Nodules
Often surmounted by a:
Pustule & Circumscribed by a rim of Erythema + Swelling
Collection of
PUS within dermis & deeper skin tissue
Primarily caused by:
STAPH Aureus
Treatment:
Incision & Drainage
addition of Systemic ABx does NOT improve cure rates
even in MRSA
What type of ABSSI?
Larger & Deeper than Furuncle
Commonly found on the:
Back of the NECK / HAIRLINE
- *CARBUNCLE = Several adjacent furuncles**
- *Purulent ABSSSI**
Primarily caused by:
STAPH Aureus
- *Typically require:**
- *Incision & Drainage**
What type of ABSSI?
Diffuse / Superficial / Spreading skin infxn
Limited to:
UPPER DERMIS
Clearly delineated borders often the FACE ONLY
- *ERYSIPELAS**
- NON-purulent ABSSI*
Primarily caused by:
- *STREPtococcus Spp_ - _B-HEMOLYTIC Group A**
- *S. Pyogenes**
Treatment:
ABx Therapy
What type of ABSSI?
3-4 Episodes of Cellulitis per YEAR
Often Caused by:
OBESITY / TINEA PEDIS
- *RECURRENT CELLULITIS**
- NON-purulent ABSSI*
Primarily caused by:
STREPtococcus Spp** - **B-HEMOLYTIC Group A
(S. Pyogenes)
B C F G
rarely Staph. Aureus
CONSIDER - ABx Prophylaxis
Oral Penicillin VK BID for 4-52 weeks
- *CARBUNCLE**
- *Purulent ABSSSI**
1st LINE TREATMENT
1st Line Treatment:
Incision & Drainage
abx unnecessary unless SYSTEMIC S/Sx of infection
What type of ABSSI?
DEEP INFECTION involving FASCIA** + **MUSCLE
- *Aggressive Subq Infxn** that tracks along:
- *Superficial Fascia**
- *SYSTEMIC TOXICITY**
- *Rapidly Advancing / Disorientation / Lethargy**
- *WOOD-HARDNESS_ + _CREPITUS**
- *Anesthesia / discoloration / PAINFUL**
- *NECROTIZING FASCIITIS**
- NON-purulent ABSSI*
POLYMICROBIAL
S. Pyogenes / S. Aureus
Aeromonas Hydrophila / Vibrio Vulnificus
- *ERYSIPELAS & CELLULITIS**
- NON-Purulent ABSSSI*
1st LINE TREATMENT
1st Line Treatment:
ABx Therapy to cover:
GROUP A STREP** = **B-HEMOLYTIC Group A
(S. Pyogenes)
PENICILLIN VK
CEPHALOSPORIN / Ceftriaxone IV / Cefalozin IV
CLINDAMYCIN
DICLOXACILLIN
What type of ABSSI?
Painful - Tender - Fluctuant Red Nodules
Often surmounted by a:
Pustule & Circumscribed by a rim of Erythema + Swelling
Collection of
PUS within dermis & deeper skin tissue
- *CUTANEOUS ABSCESS**
- *Purulent ABSSSI**
Primarily caused by:
STAPH Aureus
Treatment:
Incision & Drainage
addition of Systemic ABx does NOT improve cure rates
even in MRSA
- *CUTANEOUS ABSCESS**
- *Purulent ABSSSI**
1st LINE TREATMENT
Painful - Tender - Fluctuant Red Nodules
Often surmounted by a:
Pustule & Circumscribed by a rim of Erythema + Swelling
Collection of
PUS within dermis & deeper skin tissue
1st Line Treatment:
Incision & Drainage
addition of Systemic ABx does NOT improve cure rates
even in MRSA
Primarily caused by:
STAPH Aureus
Factors that contribute to:
PROPHYLAXIS FAILURE
for
RECURRENT CELLULITIS
3-4 Episodes of Cellulitis per Year
Oral Penicillin VK BID 4-52 weeks
> 3 Previous Cellulitis
Edema
BMI** **>** **33
- *ABX PROPHYLAXIS IS ALMOST NEVER USED**
- *FAILS VERY OFTEN**
- *Furuncles & Carbuncles**
- *Purulent ABSSSI**
CAUSED BY WHAT ORGANISM(s)?
Primarily caused by:
STAPH Aureus
TREATMENT
- *RECURRENT PURULENT ABSSSI**
- *Cutaneous Abscess / Furuncle / Carbuncle**
- *Repeated I&D**
- no clear benefit of ABx therapy*
- *Decolonization** with intranasal mupirocin
- because colonized by MRSA*
Chlorhexidine Bathing
Daily Washing of personal items
Evaluation for:
Neutrophil Disorders** or **Hidradentis Suppurative
- *NECROTIZING FASCIITIS**
- NON-Purulent ABSSSI*
1st LINE TREATMENT
SURGICAL INSPECTION** + **DEBRIDEMENT
ABx therapy until –> no more debridement needed
clinically improved / afebrile for 48-72 hours / until they are better
EMPIRIC THERAPY
- *Gram +POS+** = STREP** / **STAPH** (**MRSA)
- *VANCOMYCIN** - Linezolid - Daptomycin
- *Gram -Neg-**
- *PIP/TAZO** - Carbapenem - Ceftriaxone
- *PLUS METRONIDOZOLE**
- If suspected GAS*
- *Protein Synthesis Inhibitor**
- *FURUNCLE = BOILS**
- *Purulent ABSSSI**
1st LINE TREATMENT
Infection of the:
Hair Follicles
Superficial inflammation of Epidermis
different from folliculitis
Often:
Rupture + Drain Spontaneously
W/
MOIST HEAT
- *PURULENT ABSSSI**
- *Cutaneous / Furuncle / Carbuncle**
When would we use ANTIBIOTICS?
- *SYSTEMICALLY ILL**
- *Elevated HR / RR / TEMP / WBC**
IMMUNOCOMPROMISED
Multiple Abscesses** - **Extreme Age
Lack of RESPONSE to I&D
ABx targetting MRSA
In ADDITION to I&D