14 - URTI Flashcards

1
Q

Pathogenesis of:

ACUTE SINUSITIS

Best to get from specimen collection, but we know historical data very well for this

Nasal passages colonized –> hard to get to the STERILE SINUS

A
  • *VIRUS = MOST COMMON**
  • rarely fungi*

S-M-H
(same top 3 for CAP)

S. PNEUMONIAE

M. CATTARHALIS

H. INFLUENZAE

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2
Q

Pathogenesis of:

CHRONIC Sinusitis

Best to get from specimen collection, but we know historical data very well for this

Nasal passages colonized –> hard to get to the STERILE SINUS

A

Sinusitus that last:
> 12 WEEKS

  • less often an INFECTIOUS PROCESS:*
  • *FUNGI**
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3
Q

What type of URTI based on clinical manifestations?

Persistant Symptoms lasting > 10 days

Severe Symptoms or High Fever (> 102)
&

Purulent Nasal Discharge + Facial Pain
lasting 3-4 consecutive days @ beginning of illness

“DOUBLE SICKNESS”
New onset:
Fever / HA / ↑Nasal Discharge
following an:
initial typical viral URTI that lasted 5-6 days and was initially improving

A

ACUTE BACTERIAL SINUSITIS

WE TREAT THIS

Augmentin for Adults

Amoxicillin for Children

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4
Q

What type of URTI based on clinical manifestations?

Duration of Sx = 5-10 days
peak 3-6 days

Congestion & Discharge

Clear/Watery discharge -> Mucoid/thick/opaque ~Green

Mild fever in 48 hours

A

ACUTE SINUSITIS
w/
VIRAL ETIOLOGY

Most common –> DO NOT TREAT

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5
Q

What type of URTI based on clinical manifestations?

Triad of:
Sore Throat / Fever / Pharyngeal Inflammation

Sudden onset of:
Fever / HA / GI symptoms

ERYTHMA / TONSILLAR SWELLING / GRAY-WHITE EXUDATE
covering posteror pharynx

Lyphadenopathy = Swollen Lymphs

A
  • *GAS**
  • *GROUP A STREP - PHARYNGITIS**

Strep. Pyrogenes

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6
Q

What type of URTI based on clinical manifestations?

Triad of:
Sore Throat / Fever / Pharyngeal Inflammation

w/o any other syndromes

A

PHARYNGITIS
from
Gram Neg Anaerobes or Atypicals

DO NOT TREAT

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7
Q

What type of URTI based on clinical manifestations?

  • *Initial ​Common Cold Sx:**
  • *Nasal Congestion / Rhinitis / Sore Throat / Mailaise / mild Fever**

followed by:
Dry** or **Productive COUGH of <3 weeks duration

7-10 days
severe > 3 weeks

A

ACUTE BRONCHITIS

Cough symptoms OVERLAP with
common cold/pneumonia/asthma

DIFFICULT TO DIAGNOSE

Goal of Diagnosis:
DISCRIMINATE FROM PNEUMONIA

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8
Q

What type of URTI based on clinical manifestations?

Triad of:
Sore Throat / Fever / Pharyngeal Inflammation

Conjunctivitis

Oral Ulcers

Cough

Diarrhea

A

VIRAL PHARYNGITIS

MOST COMMON PHARYNGITIS

DO NOT TREAT

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9
Q
  • *Adjunctive Treatment of**
  • *ACUTE BACTERIAL SINUSITIS**

(PERSISTANT SYMPTOMS > 10 DAYS)
Severe Symptoms or High Fever >102
+
Purulent Nasal Discharge/Facial Pain
3-4 consecutive days @ beginning of illness

DOUBLE SICKNESS

A

STEROIDS NOT RECOMMENDED

Antihistamines + Decongestants
for underlying allergies

Saline Nasal Spray

Surgery for removal of obstructions

  • *PREVENTION**
  • *VACCINES / SMOKING CESSATION / DONT DO COCAINE :(**
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10
Q
  • *Treatment of**
  • *ACUTE BACTERIAL SINUSITIS**

(PERSISTANT SYMPTOMS > 10 DAYS)
Severe Symptoms or High Fever >102
+
Purulent Nasal Discharge/Facial Pain
3-4 consecutive days @ beginning of illness

DOUBLE SICKNESS

A

Consider 3 days observation

ADULTS:
AUGMENTIN for 5-7 Days

Children:
AMOXICILLIN for 10-14 days

Also:
Cefpodoxime / Cefixime / Cefdinir / Cefprozil
Levofloxacin / Moxifloxacin

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11
Q
  • *Treatment of**
  • *ACUTE BACTERIAL SINUSITIS**
  • *PCN ALLERGY**

(PERSISTANT SYMPTOMS > 10 DAYS)
Severe Symptoms or High Fever >102
+
Purulent Nasal Discharge/Facial Pain
3-4 consecutive days @ beginning of illness

DOUBLE SICKNESS

A

LEVOFLOXACIN** or **MOXIFLOXACIN

Normal for Acute Bacterial Sinusitis:

ADULTS:
AUGMENTIN for 5-7 Days

Children:
AMOXICILLIN for 10-14 days

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12
Q

What is

“DOUBLE SICKNESS”

A

Clinical manifestation for:
ACUTE BACTERIAL SINUSITIS

New Onset of:
FEVER / HA / ↑NASAL DISCHARGE
following initial:
Typical viral URTI lasting 5-6 days that was INITIALLY IMPROVING

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13
Q

Pathogenesis of:

PHARYNGITIS

A
  • *VIRUS = MOST COMMON**
  • *Adenovirus** - most prevelant

Group A Streptococci = Strep. Pyrogenes
most common BACTERIA
ONLY ONE THAT WE TREAT

Gram Neg Anaerobes

Atypicals

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14
Q

How do we DIAGNOSE - GAS?

Group A Strep

A

Diagnosis Table - Point System

3-14 Years = 1 point
MOST COMMON IN THIS AGE, -1 pt if 45y/o+

Temp > 38*C

Absence of Cough

Swollen / Tender anterooir Cervical NODES

TONSILLAR SWELLING or EXUDATE

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15
Q

Treatment of
GAS

Group A Strep - Pharyngitis

PCN ALLERGY

NOT FOR CHILDREN < 3
they don’t get RHEUMATIC FEVER
we ONLY treat to PREVENT POST-STREP SYNDROMES
–> can cause valvular damage

A

PCN Allergy:
Erythromycin or Azithromycin
Macrolides
or
1st gen Cephalosporin

Normal GAS treatment:

  • *AMOXICILLIN_ or _PENICILLIN VK**
  • *10 Days**
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16
Q

Treatment of
GAS

Group A Strep - Pharyngitis

NOT FOR CHILDREN < 3
they don’t get RHEUMATIC FEVER
we ONLY treat to PREVENT POST-STREP SYNDROMES
–> can cause valvular damage

A
  • *AMOXICILLIN_ or _PENICILLIN VK**
  • *10 Days**

Macrolide or Cephalosporin
alternative

Augmentin for Fusobacterium Spp.

PCN Allergy:
Erythromycin or Azithromycin or 1st gen Cephalosporin

17
Q

Pathogenesis of:

ACUTE BRONCHITIS

WE DO NOT TREAT
COUGH IS MAIN DETERMINANT

A

VIRUS
MOST COMMON - WINTER
Kids < 5 y/o

  • *Bacteria <10% of cases**
  • *Mycoplasma Pneumonia**

Chlamydia Pneumoniae

  • *Bordatella Pertussis - WHOOPING**
  • may treat to PREVENT SPREAD, not to TREAT DISEASE*
18
Q

Treatment for

ACUTE BRONCHITIS

Cough = determining factor

A

DO NOT TREAT BRONCHITIS

We diagnose mainly to:

  • *Distinguish from PNEUMONIA**
  • *Rapid antigen test** in nasopharyngeal swab for RSV/Flu
  • *X-RAY** = best way
  • *Lower Respiratory Tract = PNEUMONIA**

We can treat Symptoms of Cough:
expectorants / antihistamines / decongestants / beta2agonist

FLU = Tamiflu (Neuroamidase Inhibitors)

Bordatella pertussis –> TREAT w/ AB to DECREASE TRANSMISSION