1 - Review of Microbiology Flashcards
Sterile Sites
Areas where there are no bacteria living
NO NEED TO TREAT THESE AREAS
CNS
CV System
Upper Respiratory Tract
Bones / Joints
URINARY TRACT
Infections & Suspected Organisms of:
Pharyngitis
Group A Streptococci
Infections & Suspected Organisms of:
Acute Sinusitis
S. Pneumoniae
- *H. Influenzae**
- also Epiglottitis*
M. Catarrhalis
Same for all 4:
Otitis / Bronchitis / Acute Sinusitis / Pneumonia+
Infections & Suspected Organisms of:
Otitis
S. Pneumoniae
- *H. Influenzae**
- also Epiglottitis*
M. Catarrhalis
Same for all 4:
Otitis / Bronchitis / Acute Sinusitis / Pneumonia+
Infections & Suspected Organisms of:
Bronchitis
S. Pneumoniae
- *H. Influenzae**
- also Epiglottitis*
M. Catarrhalis
Same for all 4:
Otitis / Bronchitis / Acute Sinusitis / Pneumonia+
Infections & Suspected Organisms of:
Pneumonia
- *S. Pneumoniae / H. Influenzae /** M. Catarrhalis
- Same for all 4:
- Otitis / Bronchitis / Acute Sinusitis / Pneumonia+**
M. TUBERCULOSIS
MYCOPLASMA
VIRAL
Infections & Suspected Organisms of:
CHRONIC Sinusitis
Anaerobes
- *S. Aureus**
- also HAP & VAP*
Infections & Suspected Organisms of:
Epiglottitis
H. Influenzae
also Acute Sinusitis
Infections & Suspected Organisms of:
Hospital Acquired Pneumonia
HAP & VAP
- *S. Aureus**
- also Chronic Sinusitis*
Gram NEG Bacteria Pseudomonas
Acinetobacter
- *Klebsiela**
- often RESISTANT*
Infections & Suspected Organisms of:
Endocarditis - Subacute
S. Viridans
Infections & Suspected Organisms of:
Endocarditis - ACUTE (IVDA)
S. Aureus
Gram NEG rods
Enterococcus
Infections & Suspected Organisms of:
Endocarditis - Acute
(Prosthetic Valve)
S. Epidermidis
Infections & Suspected Organisms of:
Osteomyelitis / Septic Arthritis
S. Aureus
Streptococci
Gram NEG Rods
Infections & Suspected Organisms of:
Community UTI
E. Coli
Enterococcus
K. Pneumoniae
S. Epidermidis
S. Aureus
Infections & Suspected Organisms of:
Hospital - UTI
Enterococcus
E. Coli
Resistant Gram Negative Rods
Infections & Suspected Organisms of:
Skin & Soft Tissue Infections
Gram POS Bacteria
Staph & Strep
Infections & Suspected Organisms of:
Intra-Abdominal Infections
B. Fragilis
E. Coli
Enterococcus
Organism Classification:
Gram POS Cocci
S. Aureus
S. Epidermidis
Streptococci
SSS - Pos Cocci
Organism Classification:
Gram NEG Cocci
Gonococcus
Meningococcus
GM -Gram Neg Cocci
Organism Classification:
Gram POS Bacilli
Anthrax
Listeria Monocytogenes
Clostridium Perfringens
Corynebacterium Diptheria
ALCC - Pos Bacilli
Organism Classification:
Gram NEG Bacilli
BH - FAP + Enterobacteraciae
Bacteroides
Haemophilus
Fusobacterium
Acinetobacter
Pseudomonas
E. Coli / Enterobacter / Klebsiella
Organism Classification:
Enterobacteraciae
GRAM NEG BACILLI
BH-FAP+Enterobacteraciae
E. Coli
Enterobacter
Klebsiella
EEK
can be resistant to 5 drugs
Organism Classification:
Anaerobes
PCB = People Cant Breathe
ANAEROBES
Peptostreptococcus
Clostridium spp.
Bacteroides spp.
Molecular Rapid Diagnostic Tests (RDTs)
Culture Independent
Direct Antigen Detection Tests
POC tests for respiratory viruses & group A strep
NAATs = Nucleic Acid Amp Tests
Syndromic multiplex PCR panels
PCR-based direct detection
Molecular Rapid Diagnostic Tests (RDTs)
Culture Dependent
Rapid BioChem IDentification
MALDI-TOF-MS
Proteomic ID
Blood Culture IDentification
BCID microarrays / PNA-Fish
Rapid Phenotypic AST
NAAT detection
Biological Confirmation
of Rapid Diagnostic Test (1-2 hours)
Requires lb with minimul culture / immunoassay equipment
Requires time:
Bacterial culture = 24-72 hours
ID = 4-24 Hours
AB susceptibility testing = 24 hrs
ELISA = 2-4 hours
Fungi Classification:
YEAST = Candida spp.
Single-celled fungi
Flourish in moist environments
&
often part of normal flora (GI tract & female genital tract)
Fungi Classification:
Molds = Aspergillus
Multicellular
Dermatophytes
Trichophyton spp. Microsporum spp. Fusarium
Found in:
Soil / Food / Decomposing organic matter
Fungi Classification:
- *Dimorphic Fungi**
- *Blastomyces / Histoplasma**
Capable to grow as
EITHER
Mold or Yeast
Infections Caused by
Dermatophytes
Scalp Ringworm = Tinea Capitis
Beard Ringworm = Tinea Barbae
Tinea Versicolor
Tinea Corpori
Tinea Pedis / Athletes foot
Parasitic Diseases
2 Groups
Protozoan
Malaria / Amebiasis / Giardiasis / Toxoplasmosis
Leishmaniasis / Trypanosomiasis
Helminthic
WORMS
Enterobiasis = Pinworm // Cestodiasis = Tapeworm
Ascariasis = Roundworm // Trichuriasis = Whipworm
Routes by Which Humans Acquire Parasitic Infections
EYES
Contact & Penetration
Inhalation
Vector-Borne
from bugs / mosquitos / flies
Fecal-Oral Ingestion
SKIN
COntact & penetration
Sexual Contact
- *Ascaris Lumbricoides**
- *GIANT ROUND WORM**
1 of the most common:
Intestinal Worm Infections
Associated with:
Poor personal hygiene / sanitation
human feces = fertilizer
Prion Disease
Prion = Infectious Proteins
Normal body proteins –> alternate configuration
from contact w/ other prion proteins
no DNA or RNA
Most common in humans/mammals = PrP
Prion forms insoluble deposits in BRAIN –> neurons rapidly degenerate
Human Prion Diseases
- *CJD**
- *Creutzfeldt Jakob Disease**
vCJD
Gerstmann-Straussler-Scheinker Syndrome
Fatal Familial Insomnia
KURU
brain eating in New Guinea
Animal Prion Diseases
MAD COW DISEASE
- *BSE**
- *Bovine Spongiform Encephalopathy**
- *CWD**
- *Chronic Wasting Disease**
Scrapie
Transmissible mink / Feline Spongiform / Ungulate Spongiform
ENCEPHALOPATHIES