210b pathology

Question 1

histo - proliferative endometrium

Answer 1

due to E –> increased endometrial tissue

basalis is bottom later with stem cells
top 2/3 is functionalis –> few tubular glands coiled with a lot of stroma

glands are punched out tubules w/ psuedostatrised nuclei - small and round with freq mitosis

Question 2

histo - secretory endometrium

Answer 2

due to P from corpus luteum

day 16/17 early - subnuc vacuoles, stromal edema day 18/19 mid - supranuc vacuoles, spiral arteries
day 21/11 late - vacuoles secreted in lumen, no more mitosis

day 22 - secretory endometrium is 2-5 x thicker than proliferative endo w/ saw-tooth arrangment of glands; hyper secretory

day 23/24 -

menstrual

Question 3

histo - menstrual endometrium

Answer 3

lack of P due to loss of corpus luteum

lymphocytes invade, diffuse stromal and epi break down

Question 4

histo - endometriosis

Answer 4

endomeetrial tissue to other tissue other than uterus

Question 5

histo - adenomyosis

Answer 5

endometrial tissue in myometrium –> thickens myometrium, black from blood; endo tissue appears normal

pain, bleeding, infertility -> hysterectomy

Question 6

normal menstrual cycle - phases + hormone

Answer 6

proliferative (E) –> ovulation (w/ high LH) –> secretory/luteal (P) –> menstrual (lack of P)