21- Schizophrenia Flashcards
What is schizophrenia?
What are the three classes in to which schizophrenia symptoms can be grouped?
What schizophrenia symptoms are classed as positive?
What schizophrenia symptoms are classed as negative?
What schizophrenia symptoms are classed as cognitive?
How is schizophrenia diagnosed?
Describe in detail the symptoms of schizophrenia
How many phases are there in schizophrenia? What are they?
What is the prodrome?
What is the active/acute phase?
What is remission?
What is schizophreniform?
What is the aetiology of schizophrenia?
What do twin studies tell us about schizophrenia?
What are candidate genes?
What is the role of genetics in the aetiology of schizophrenia?
What kind of stresses can contribute to schizophrenia?
Describe the role of environmental factors in the aetiology of schizophrenia
What are the pathophysiology’s of schizophrenia?
What dopamine pathways is schizophrenia associated with?
What is the dopamine hypothesis of schizophrenia?
What is the evidence against and for the dopamine hypothesis for schizophrenia?
Describe the brain abnormalities in the brain structures of schizophrenics
What is hypo frontality?
How is NMDA receptor hypoactivity related to schizophrenia?
What is the role of 5HT and what is its role in schizophrenics?
What are the main current theories underlying the pathophysiology’s of schizophrenia?
What are the treatment options available for schizophrenia?
What are the main dopamine pathways?
What are the two classes of antipsychotics?
Compare typical and atypical antipsychotics
What is the effect of D2 receptor blockade in the mesolimbic system?
What is the effect of D2 receptor blockade in the nigro-striatal?
What is the effect of D2 receptor blockade in the pituitary gland?
What is the effect of D2 receptor blockade in the nucleus accumbens?
What other receptors can antipsychotics block and what is the effect of this?
How do antipsychotics cause sedation?
What are the effects of an increase in prolactin?
What is the effect of alpha-1 adrenoreceptor antagonism of antipsychotics?
What are the anticholinergic effects of antipsychotics?
