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Physiology- The Nervous System > 21- Schizophrenia > Flashcards

21- Schizophrenia Flashcards

1
Q

What is schizophrenia?

A
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2
Q

What are the three classes in to which schizophrenia symptoms can be grouped?

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3
Q

What schizophrenia symptoms are classed as positive?

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4
Q

What schizophrenia symptoms are classed as negative?

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5
Q

What schizophrenia symptoms are classed as cognitive?

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6
Q

How is schizophrenia diagnosed?

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7
Q

Describe in detail the symptoms of schizophrenia

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8
Q

How many phases are there in schizophrenia? What are they?

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9
Q

What is the prodrome?

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10
Q

What is the active/acute phase?

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11
Q

What is remission?

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12
Q

What is schizophreniform?

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13
Q

What is the aetiology of schizophrenia?

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14
Q

What do twin studies tell us about schizophrenia?

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15
Q

What are candidate genes?

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16
Q

What is the role of genetics in the aetiology of schizophrenia?

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17
Q

What kind of stresses can contribute to schizophrenia?

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18
Q

Describe the role of environmental factors in the aetiology of schizophrenia

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19
Q

What are the pathophysiology’s of schizophrenia?

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20
Q

What dopamine pathways is schizophrenia associated with?

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21
Q

What is the dopamine hypothesis of schizophrenia?

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22
Q

What is the evidence against and for the dopamine hypothesis for schizophrenia?

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23
Q

Describe the brain abnormalities in the brain structures of schizophrenics

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24
Q

What is hypo frontality?

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25
Q

How is NMDA receptor hypoactivity related to schizophrenia?

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26
Q

What is the role of 5HT and what is its role in schizophrenics?

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27
Q

What are the main current theories underlying the pathophysiology’s of schizophrenia?

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28
Q

What are the treatment options available for schizophrenia?

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29
Q

What are the main dopamine pathways?

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30
Q

What are the two classes of antipsychotics?

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31
Q

Compare typical and atypical antipsychotics

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32
Q

What is the effect of D2 receptor blockade in the mesolimbic system?

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33
Q

What is the effect of D2 receptor blockade in the nigro-striatal?

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34
Q

What is the effect of D2 receptor blockade in the pituitary gland?

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35
Q

What is the effect of D2 receptor blockade in the nucleus accumbens?

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36
Q

What other receptors can antipsychotics block and what is the effect of this?

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37
Q

How do antipsychotics cause sedation?

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38
Q

What are the effects of an increase in prolactin?

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39
Q

What is the effect of alpha-1 adrenoreceptor antagonism of antipsychotics?

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40
Q

What are the anticholinergic effects of antipsychotics?

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Physiology- The Nervous System (21 decks)

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