20.1 - the structure of the nucleotide Flashcards
what are the 2 types of nucleic acids that are important to the cell
DNA (deoxyribonucleic acid)
RNA (ribonucleic acid)
DNA
carries all of the genetic information for an organism
RNA
interprets the genetic information into proteins that will carry out the essential cellular functions
what are the components of these nucleic acids
5 C sugar
phosphate
4 heterocyclic amines called nitrogenous bases.
what is the sugar in DNA
2′-deoxyribose
what is the sugar in RNA
ribose
what is the difference between 2′-deoxyribose and ribose
absence of a hydroxyl group at the carbon-2 position of 2′-deoxyribose
The nitrogenous bases are divided into two families known as
pyrimidines
purines
The pyrimidine bases in DNA are
cytosine and thymine
The pyrimidines found in RNA are
cytosine and uracil
The major purines of both DNA and RNA are
adenine and guanine
As with the pyrimidines, the purines differ from one another only in
the location of functional groups around the ring.
Nucleosides are produced by the combination of a _____, either ____(in RNA) or _____ (in DNA), with a ____ or a _____base.
Sugar ribose 2'-deoxyribose purine pyrimidine
the ring atoms of the sugar are designated with a _____ to distinguish them from atoms in the ___
prime
base
The covalent bond between the sugar and the base is called a
β-N-glycosidic linkage
____________participate in the glycosidic bonds of nucleosides
N-l of pyrimidines and N-9 of purines
The nucleosides formed with ribose and adenine or guanine are called
adenosine or guanosine
If 2′-deoxyribose is the sugar in these nucleosides, they are called (adenine and guanine)
2′-deoxyadenosine and 2′-deoxyguanosine.
The ribonucleosides formed from cytosine and uracil are called
cytidine and uridine
The deoxyribonucleosides of cytosine and thymine are called
2′-deoxycytidine and thymidine
deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are
long polymers of nucleotides.
Each nucleotide consists of
a five-carbon sugar (either ribose or deoxyribose)
one of the five nitrogenous bases,
one or more phosphoryl groups
A nucleotide with the sugar ribose is a _______-, and one having the sugar 2′-deoxyribose is a __________
ribonucleotide
deoxyribonucleotide
The covalent bond between the sugar and the phosphoryl group is a _____ bond formed by a ______reaction between the ____ of the ____and an ____ of the ____group.
phosphoester
condensation
5’-OH sugar
OH phosphoryl
the bond between the base and the sugar is a β-N-glycosidic linkage that joins the _____ of the sugar and a nitrogen atom of the base (___ of purines and ___ of pyrimidines).
1′-carbon
N-9
N-1
Remove the -ine ending, and replace it with either
- osine purines
- idine pyrimidines
For a deoxyribonucleotide, the prefix deoxy- is placed
before the modified nitrogenous base name.
Add a prefix to indicate the number of ____ groups that are attached
phosphoryl