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CS1 Exam 2 > 20- Vasculopathies > Flashcards

20- Vasculopathies Flashcards

1
Q

affects nordics over 50 specifically in the arteries of the head

A

temporal (giant cell) arteritis

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2
Q

pathology of temporal (giant cell) arteritis

A

granulomatous inflammation (HLA-DR associated) and T-cell mediated

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3
Q

“pulseless disease”

A

takayasu arteritis

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4
Q

granulomatous vasculitis of medium and large arteries (esp. arotic archand branches) also pulmonary, coronary, and renal arteries predominantly females under age 40

A

takayasu arteritis

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5
Q

characterized by ocular disturbances and weakening of pulses in upper extremities

A

takayasu arteritis

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6
Q

systemic necrotizing vasculitis of small and medium-sized arteries producing infarcts

A

polyarteritis nodosa PAN

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7
Q

pathology of polyarteritis nodosa

A

type III immune injury involving immune complexes (associated with he B and C)

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8
Q

is there pulmonary involvement with polarteritis nodosa?

A

no

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9
Q

observe beaded appearance of renal a. and melena

A

polyarteritis nodosa

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10
Q

afflicting asian infants, skin rash and peeling with coronary a. aneurysm

A

kawasaki disease

aka mucocutaneous lymph node syndrome

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11
Q

kawasaki disease diagnostic criteria

A

fever greater than 5 days and 4/5 CREAM

conjunctiviits
rash
edema
adenopathy
mucosal involvement
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12
Q

saddle nose disfigurement and granuloma lesions in lung tissue

A

granulomatosis with polyangitis

aka
Wegener

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13
Q

triad of symptoms for granulomatosis with polyangitis

A
  1. necrotizing granulomas of upper respiratory tract
  2. granulomatous vasculitis of medium and small vessels
  3. necrotizing often crescentic glomerulonephritis
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14
Q

PR3 ANCA+ 95% cases

A

wgener’s granulomatosis

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15
Q

MPO-ANCA + 50% cases

A

churg-strauss syndrome

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16
Q

small vessel necrotizing vasculits associated with asthma, allergic rhinitis and lung infiltrates

A

churg strauss sndrome

17
Q

pahtology of churg-strauss syndrome

A

peripheral hypereosinophilia and extravascular necrotizing granulomata

18
Q

vascular insufficiency of tibial and radial arteries due to thrommbosing acute and chronic inflammation

A

buerger’s disease

aka thromboangiitis obliterans

19
Q

caused by hypersensitivity to tobacco

A

buerger’s disease

aka thromboangiitis obliterans

20
Q

what do SLE, RA, henoch-schonlein purpura and cryoglobulinemia all have in common?

A

immune complex mediated vasculitides

21
Q

localized abnormal dilation of any vessel

22
Q

vessel most affected by aneurysms

23
Q

true v. false aneurysm

A

t: retains all three layers of vessel wall at affected site
f: intima and media damaged, only adventitia remains

24
Q

aneurysm on one side only

A

saccular

fusiform is the term for the entire vessel aneurysm

25
Q

type of aneurysm typically between renal arteries and bifurcation

A

atherosclerotic aneurysm

26
Q

type of aneurysm typically at thoracic aorta and arch, a manifestation of tertiary syphillis

A

syphilitic aneurysm

27
Q

false aneurysm from inflammatory damage

A

infective aneurysm aka mycotic aneurysm

28
Q

congenital aneurysm in the circle of willis

A

berry aneurysm

29
Q

false channel of blood coursing within vessel wall itself

A

aortic dissection

30
Q

disruption and fragmentation of elastic lamellae of the arterial media

A

cystic medial necrosis

31
Q

malformations present frombirth composed of dilated capillaries and veins in skin and oral cavity

A

herediatry hemorrhagic telangiectasia

32
Q

radiating subcutaneous arteries ofter associated with cirrhosis of liver

A

spider telaniectasia

33
Q

painful tumor under firgertips or toenails

A

glomus tumor aka glomangioma

34
Q

low grade malignant tumor of blood vessel

A

hemangioendothelioma

35
Q

malignant tumor of blood vessels from pericytes

A

hemangiopericytoma

36
Q

malignant tumor of blood vessel from carcinogen exposure

A

angiosarcoma

37
Q

red-purple macules on the skin associated with herpes virus type 8

A

kaposi’s sarcoma

38
Q

red, purple, or blue edematous soft tissue lesions that are caused by ricketssiae like organisms

A

bacillary angiomas

39
Q

4 complications of varicose veins

A
  • phlebitis
  • varicose eczema
  • DVT
  • leg ulcers

CS1 Exam 2 (17 decks)

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