2: Rhinitis and Nasal Polyps Flashcards
Define rhinitis
Inflammation of the nasal mucosa
What are the two broad categories of rhinitis
- Allergic
- Infectious
What is allergic rhinitis
IgE-mediated type I hypersensitivity reaction
What are the two-types of non-allergic rhinitis
Vasomotor
Infective
What is infectious rhinitis
Inflammation nasal mucosa due to infection
What is vasomotor rhinitis
Inflammation nasal mucosa due to changes in sympathetic-parasympathetic NS, hormones
What are causes of vasomotor rhinitis
- Cold weather
- Medications (ACEi, B-blockers)
- COCP
- Hypothyroidism
What are risk factors for allergic rhinitis
Personal or family history of atopy
How does rhinitis present clinically
- Post-nasal drip
- Congestion
- Sneezing
- Rhinorrhoea
What may long-standing rhinitis increase the risk of
Sinusitis
Otitis media
What are additional symptoms of allergic rhinitis
- Allergic conjunctivitis
- Itching throat
- Atopic dermatitis
What is a sign of long-standing vasomotor rhinitis
Enlarged turbinates
How is rhinitis usually diagnosed
Clinically
What is indicated for allergic rhinitis
Allergy Testing: skin prick or serum-specific IgE
What is first line for allergic rhinitis
Intra-nasal anti-histamine
Intra-nasal decongestants (Oxymetazoline)
what is the MOA of oxymetazoline
a1 antagonist
how long should oxymetazoline be given for
3d
why is oxymetazoline given for maximum 3d
as on withdrawal it can cause rebound nasal congestion
what is rebound nasal congestion called
rhinitis medicamentosa
how is vasomotor rhinitis addressed conservatively
medication review - stop offending medications
how is vasomotor rhinitis addressed medically
Topical nasal decongestants
how is vasomotor rhinitis addressed surgically
Resection of enlarged turbinates
Why are nasal polyps considered on a spectrum of rhinosinutitus
As they are caused by chronic inflammation and thickening of the nasal mucosa
What are nasal polyps
Oedema of nasal mucosa which then prolapses
What are nasal polyps often called
Chronic rhinosinusitus with nasal polyps
What is the typical age-range for nasal polyps
Males >40
What are the symptoms of nasal polyps
- Watery anterior rhinorrhoea
- Purulent post-nasal drip
- Nasal obstruction
- Mouth breathing
- Snoring
How do polyps usually appear
Bilateral
Adjacent to middle meatus
What triad is associated with nasal polyps
Samter’s triad
What is samter’s triad
- Aspirin Hypersensivity
- Late-Onset Asthma
- Nasal polyps
What is used to investigate nasal polyps
Anterior Rhinoscopy
How can nasal polyps be differentiated from turbinates on anterior rhinos copy
Polyps:
- Pink
- Mobile
- Non-tender
Turbinates:
- Pale
- Non-mobile
- Insensitive
If a polyp is unilateral what is required and why
Biopsy - risk nasopharyngeal cancer
When are nasal polyps rare
Children
What is a nasal polyp in a child likely to be
CF, mucocele, neoplasm
What 3 medications are given in medical management of nasal polyps
- Intra-nasal betamethaosone
- Intra-nasal fluticasone
- Doxycycline
What surgical procedure is indicated for nasal polyps
Functional endoscopic sinus surgery (FESS)
If more than a polypectomy is indicated, what imaging is required
CT
What are complications of functional endoscopic sinus surgery
Optic.N damage
CSF Leak
What is the criteria for rhinosinusitus
Nasal congestion and one of
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Pain in face
Endoscopy
Discharge
ALl remember CT findings
Smell loss
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how can rhinosinusitus be divided
Acute or Chronic
what defines chronic rhinosinusitus
> 12W
Define acute rhinosinusitus
Inflammation of nasal passage and paranasal sinuses lasting less than 12W
What are the 3 types of acute rhinosinusitus
Viral
Post-Viral
Bacterial
What are the 2 viral causes of acute rhinosinusitus
Coronavirus
Rhinovirus
What causes post-viral rhinosinusitus
Residual inflammation following viral infection
What causes bacterial rhinosinusitus
Often viral infection causes inflammation predisposing to secondary bacterial infection
What are risk factors for bacterial rhinosinusitus
- Virus
Direct spread:
- Dental infection
- Swimming
Odd anatomy:
- Septal deviation
- Large ethmoidal bull
- Mechanical ventilation
What is the diagnostic criteria for acute rhinosinusitus
Onset of two or more of the following:
- Congestion
- Discharge
- Facial Pain
- Loss sense smell
What factors indicate bacterial rhinosinusitus
Local pain
Purulent discharge
Worsening after improvement (post-viral)
How is rhinosinusitus usually diagnosed
Clinically
If rhinosinusitus persists beyond 10-days, who should the person be referred to
Refer to ENT
What may ENT order to investigate rhinosinusitus
- Nasal endoscopy
- CT paranasal sinuses
If symptoms less than 5d, how is someone with rhinosinusitus managed
Analgesia
Nasal decongestant
What is used as a nasal decongestant
Oxymetazoline
If symptoms 5-10d, what is used to manage rhinosinusitus
Nasal Steroid
Oral Abx
If symptoms persist beyond 10d what should be done
Refer ENT: CT paranasal sinus, nasal endoscopy.
IV Abx
Oral steroids
Surgery
Give 5 complications of rhinosinusitus
Abscess Osteomyelitis Intracranial abscess Venous sinus thrombosis Pre-septal cellulitus Orbital cellulitus Pott's puffy tumour
What is pre-septal cellulitis also known as
Peri-orbital cellulitus
What is the most common cause of orbital cellulitis
Rhinosinusitus
What is the commonest cause of abscess
Rhinosinusitus
What is the problem with osteomyelitis secondary to rhinosinusitus
Can spread to cause intracranial infection
What is Pott’s Puffy Tumour
Osteomyelitis of the frontal sinus
How will Potts Puffy Tumour present
Boggy forehead swelling
What is orbital cellulitis
Infection soft-tissue posterior to orbital septum
How does orbital cellulitis typically occur
Secondary to paranasal sinus infection
How will orbital cellulitis present clinically
child with:
- Inflammation
- Lid swelling
- Diplopia on eye movements
- Fever
What is a complication of orbital cellulitis
- Abscess
- Intracranial extension
Why may orbital cellulitis cause loss of vision
Optic neuritis
How can orbital cellulitis be distinguished from peri-orbital cellulitis
Proptosis Painful eye movements Visual loss Loss colour vision RAPD
How is orbital cellulitis managed in adults
IV Tazocin
How is orbital cellulitis managed in children
IV Co-amoxiclav
What investigation should be ordered in orbital cellulitis
CT
What is chronic rhinosinusitus
Inflammation mucosa of nose and paranasal sinuses for more than 12W
What are the two types of chronic rhinosinusitus
With and Without Polyps
What increases the risk of chronic rhinosinusitus
Samters triad: aspirin sensitivity, late-onset asthma
Ciliary dysfunction:
- Primary ciliary dyskinesia
- Cystic fibrosis
What is the criteria to diagnose chronic rhinosinusitus
2 or more for 12W:
- Congestion
- Discharge
- Pain
- Smell loss
What is first-line for chronic rhinosinusitus
Nasal endoscopy
to make a diagnosis of rhinosinusitus on nasal endoscopy what must be present
- Inflammation
- Polyp
- Mucopurulent discharge
- Mucosal occlusion middle meatus
What scoring system is used to grade severity of chronic rhinosinusitus
Visual analogue score
How are visual analogue score 0-3 managed
- Nasal Saline
- Intra-nasal corticosteroids
How are visual analogue score >3 managed
- Antibiotics
- Intranasal corticosteroids
- CT
- FESS
What is a complication of chronic rhinosinusitus
Mucocoele
Where are mucoceles more common
Frontal sinus
How do mucoceles present
Lump on the head
What is the risk of mucocoeles
Eroding bone