2 - Proteins Flashcards
are polymers of amino acids
Proteins
What are the structures of amino acids
B-pleated sheet
a-helix
what does amino acids contains in ff. chemical groups attached to an alpha carbon a-carbon
Amino group
Carboxyl group
Side chain group (R)
Gives the identity to amino acid
Side chain group (R)
What amino acid that does not have at least one stereocenter and is achiral
Glycine
have at least one stereocenter (a-C) and are chiral (stereoisomers)
Amino acids
What are the two stereoisomers of amino acid
L- and D-amino acid
Majority of amino acids are in L- configuration
molecules that contain both positive and
negative charges
ZWITTERION
proton donor
Bronsted Acid
proton acceptor
Bronsted Base
yields the different ionization states of amino acids
TITRATION OF AMINO ACIDS
the pH at which the net charge of an amino acid/peptide is zero
Isoelectric pH (pI)
formula for Isoelectric pH (pI)
pI = pKa1 + pKa2/2
amide bond between the alpha -carboxyl group of one amino acid and the alpha - amino group of another amino acid
PEPTIDE BOND
What are the characteristics of the Peptide bond
Partial double bond character
Planar