2 - Metabolic Syndrome (fast deck) Flashcards

1
Q

IDF worldwide definition of metabolic syndrome

A

A cluster of the most dangerous heart attack risk factors: diabetes and prediabetes, abdominal obesity, high cholesterol and high blood pressure.

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2
Q

Classical risk factors for global cardiometabolic risk

A

High blood glucose, smoking, high LDL, and hypertension.

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3
Q

Emerging classical risk factors for global cardiometabolic risk

A

Insulin resistance, low HDL, high triglycerides, and inflammatory markers.

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4
Q

Where is insulin produced and what does it do?

A

Produced in the pancreas. Allows cells to take in glucose to use for energy.

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5
Q

What is insulin resistance?

A

Cells no longer respond to insulin, therefore glucose can’t enter the cells.

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6
Q

What are the two most significant risk factors for metabolic syndrome?

A

Insulin resistance and central obesity.

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7
Q

How does age relate to metabolic syndrome risk?

A

The prevalence of metabolic syndrome increases with age.

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8
Q

How many people in their 20s does metabolic syndrome affect?

A

Less than 10%

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9
Q

How many people in their 60s does metabolic syndrome affect?

A

40%

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10
Q

What races/ethnic groups are at higher risk of metabolic syndrome?

A

African-americans and mexican-americans.

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11
Q

What BMI increases the risk of metabolic syndrome?

A

BMI 25+

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12
Q

What type of fat increases the risk of metabolic syndrome?

A

Abdominal fat.

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13
Q

What types of histories increase a person’s risk of metabolic syndrome?

A

Family history, history of type 2 diabetes, history of diabetes during pregnancy

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14
Q

What other diseases increase the risk of metabolic syndrome?

A

Hypertension, CVD, and polycystic ovary syndrome.

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15
Q

Risk ratio of 1

A

Suggests no difference or little difference in risk

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16
Q

Risk ratio of less than 1

A

Reduced risk in the exposed group

17
Q

Risk ratio of more than 1

A

Increased risk of outcome in the exposed group

18
Q

Odds ratio of 1

A

Exposure does not affect the odds of outcome.

19
Q

Odds ratio of less than 1

A

Exposure lowers the odds of outcome.

20
Q

Odds ratio of more than 1

A

Exposure raises the odds of outcome.

21
Q

The incidence of metabolic syndrome increases with…

A

Age and obesity.

22
Q

Three concepts of underlying causes responsible for the epidemic of metabolic syndrome…

A

Environmental causes, insulin resistance, and inflammation.

23
Q

Primary prevention lifestyle changes for metabolic syndrome…

A

Weight reduction, change in dietary choices, and increase in physical activity.

24
Q

Secondary prevention screening for metabolic syndrome (types)

A

Blood sugar, A1C, lipids, and blood pressure.

25
Q

Goal of tertiary prevention of metabolic syndrome.

A

Minimize risk of type 2 diabetes and cardiovascular disease by treating the following components: obesity, glucose intolerance, insulin resistance, lipid disorders and hypertension.