2. Lincosamides Flashcards
1
Q
Example of a Lincosamide
A
Clindamycin
2
Q
Lincosamide mechanism of action
A
Prevents protein synthesis so is bacterostatic
3
Q
Clindamycin spectrum of actvity
A
Clindamycin is active against anaerobes and gram positive cocci (streptococci, MRSA)
4
Q
Clindamycin indications
A
Treats MRSA infections and bone and joint infections caused by staphylococci
5
Q
Clindamycin side effects
A
Most likely causes colitis (severe, prolonged or bloody diarrhoea). Patients must STOP the antibiotic if this is observed