2. Carbapenems Flashcards
1
Q
Bacteria that carbapenems are active against??
A
Gram positive, gram negative and anaerobes
2
Q
Examples of carbapenems
A
Imipenem, meropenem
3
Q
Carbapenems are not active against…
A
methicillin-reistsant staphylococcus aureus (MRSA) and enterococcus faecium
4
Q
Which carbapenem is given with cilastatin and why?
A
Imipenem, as it is partially inactivated in the kidney by enzymes therefore cilastatin will inhibit these enzymes to block its renal metabolism.
5
Q
Common side effects of carbapenems
A
6
Q
What is Meropenem and Ertapenem administered with?
A
Nothing, they are stable to renal enzymes
7
Q
Carbapenems are broad spectrum or narrow spectrum
A
Broad-spectrum
