2/23 Rx: Drug Abuse Class Qs

Question 1

This drug is sometimes used to dec alcohol cravings in alcoholics

Answer 1

naloxone (segmental area involved)

Question 2

this drug acts mainly by increasing the non-vesicular release of dopamine from dopaminergic neurons

Answer 2

amphetamine (prevents the packaging)

Question 3

the elimination of this drug follows mainly zero-order kinetics

Answer 3

ethanol

Question 4

this drug is used in heroin detoxification programs

Answer 4

buprenorphine, naloxone

Question 5

an 18 y/o girl who had never used recd rugs joined in smoking multiple marijuana cigs at a party. which of the following signs and sx would the girl most likely experience just after smoking?

Answer 5

inc HR, blood shot eyes

Question 6

22 y/o man: CC= muscle aches, nausea, anxiety. reported as a heroin addict and had been smoking phencyclidine occasionally for the past 6 months. He was sweating, shaking, kept yawning. PE= hyperventilation, hypothermia, high BP, tachycardia. pupils dilated, no nystagmus. Which of the following drugs would be most appropriate to provide immediate relief to this pt?

Answer 6

Mu receptor agonist

Question 7

17 y/o girl who had never used drugs smoked drug cigs. In the firsts 5 min, she experienced uncontrollable laughter, depersonalization, and sharpened vision. The concentration became difficult, and she noticed that her heart was “pounding”. her friends noticed reddening of her conjunctiva but no change in diameter. Drug?

Answer 7

Cannabis

Question 8

50 y/o homeless man brought to ER after found disoriented and trembling under a bridge. PE and vitals–> delirium tremens. which of the following s/sx will pt show?

Answer 8

visual hallucinations

Question 9

23 y/o man brought to ER for combative behavior. Took rec drugs pills. pt was agitated, diaphragmatic, and disorientated. BP 170/100, P 139, T 101˚, Pupils= meiotic, reactive to light, vertical and horizontal nystagmus. Drug?

Answer 9

phencyclidine

hallucinations upon withdrawal

Question 10

3 y/o boy brought to ER w/severe vomiting after having ingested antifreeze mixture containing ethylene glycol. the purpose of ethanol tx in this pt

Answer 10

retards the oxidation of ethylene glycol to its toxic metabolites.

Question 11

23 y/o man found dead. pt was a drug user and tries different drugs. autopsy- blood level of morphine substantially lower than the estimated minimum lethal conc. they are sure that death was caused by concomitant admin of another drug.. what other drug was involved?

Answer 11

ethanol (coma, pinpoint pupils)

Question 12

how to tx cocaine?

Answer 12

BNZs as needed