2/18: Drug Syndromes-- Chart Summary Flashcards

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1
Q

SS + Rx history

A

pro-serotonergic drug

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2
Q

SS + time for condition to develop

A

<12 hrs

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3
Q

SS + vital signs

A

HTN, tachycardia, tachypnea, hyperthermia (>41.1˚C)

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4
Q

SS + pupils/mucosa/skin

A

mydriasis, sialorrhea (excessive drooling), diaphoresis

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5
Q

SS + bowel sounds

A

hyperactive

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6
Q

SS + neuromuscular tone

A

inc, predominately in lower extremities

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7
Q

SS + neuromuscular reflexes

A

hyperreflexia clonus (unless masked by inc muscle tone)

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8
Q

SS + mental status

A

agitation, coma

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9
Q

anticholinergic “toxidrome” + Rx Hx

A

anti-cholinergic agent

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10
Q

anticholinergic “toxidrome” + time for condition to develop

A

<12 hrs

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11
Q

anticholinergic “toxidrome” + vital signs

A

HTN (mild), tachycardia, tachypnea, hyperthermia (<38.8˚C)

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12
Q

anticholinergic “toxidrome” + pupils/mucosa/skin

A

mydriasis / dry erythema hot and dry to touch

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13
Q

anticholinergic “toxidrome” + bowel sounds

A

dec or absent

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14
Q

anticholinergic “toxidrome” + neuromuscular tone

A

normal

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15
Q

anticholinergic “toxidrome” + neuromuscular reflexes

A

normal

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16
Q

anticholinergic “toxidrome” + mental status

A

agitated, delirium

17
Q

neuroleptic malignant syndrome + Rx Hx

A

dopamine antagonist

18
Q

neuroleptic malignant syndrome + time for condition to develop

A

1-3 days

19
Q

neuroleptic malignant syndrome + vital signs

A

HTN, tachycardia, tachypnea, hyperthermia (>41.1˚C)

20
Q

neuroleptic malignant syndrome + pupil/mucosa/skin

A

normal / sialorrhea / pallor, diaphoresis

21
Q

neuroleptic malignant syndrome + bowel sounds

A

normal or dec

22
Q

neuroleptic malignant syndrome + neuromuscular tone

A

“lead-pipe” rigidity present in all muscle groups

23
Q

neuroleptic malignant syndrome + neuromuscular reflexes

A

bradyreflexia

24
Q

neuroleptic malignant syndrome + mental status

A

stupor, alert mutism, coma

25
Q

malignant hyperthermia + Rx Hx

A

inhalational anesthesia (INHA)

26
Q

malignant hyperthermia + time for condition to develop

A

30 min - 24 hr after admin of INHA or succinylcholine

27
Q

malignant hyperthermia + vital signs

A

HTN, tachycardia, tachypnea, hyperthermia (can be as high as 46˚C)

28
Q

malignant hyperthermia + pupils/mucosa/skin

A

normal / normal / mottled appearance, diaphoresis

29
Q

malignant hyperthermia + bowel sounds

A

decreased

30
Q

malignant hyperthermia + neuromuscular tone

A

“rigor mortis” like rigidity

31
Q

malignant hyperthermia + neuromuscular reflexes

A

hyporeflexia

32
Q

malignant hyperthermia + mental status

A

agitation