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DEN 7101S Human Structure and Function II > 2/2 Exam 2 Howard Lymphatic System > Flashcards

2/2 Exam 2 Howard Lymphatic System Flashcards

1
Q

Functions of the lymphatic system

A
  • Immunity
  • Lipid absorption
  • Maintain fluid balance
  • Clean fluid back to blood
  • Removes excess fluid from tissues
  • Removes cellular debris
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2
Q

The lymphatic system is associated with the _____ system

A

Immune system

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3
Q

What are the two components of the immune system?

A

Innate and adaptive

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4
Q

Properties of the innate immune system

A
  • Rapid
  • Nonspecific
  • No memory
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5
Q

Properties of the adaptive immune system

A
  • Specificity, diversity, memory, self/non-self recognition
  • Slower
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6
Q

Critical components of the adaptive immune system

A

B and T lymphocytes

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7
Q

The innate immune system “sees”:

A

Pathogen-associated molecular patterns (PAMP)

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8
Q

Critical components of the innate immune system

A
  • Complement
  • Toll-like receptors (TLR’s)
  • Mast cells
  • Eosinophils
  • Neutrophils
  • Macrophages
  • Natural killer cells
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9
Q

Example of a PAMP

A

LPS

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10
Q

What cells are associated with the adaptive immune system?

A
  • Antigen presenting cells
  • Natural killer cells (?)
  • Clones of T lymphocytes (T cells)
  • Clones of B lymphocytes (B cells)
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11
Q

____ are associated with cell-mediated immune response (cytotoxic)

A

T cells

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12
Q

____ are associated with humoral immune response (antibodies)

A

B cells

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13
Q

What are the two types of lymphoid organs?

A
  • Primary (central)
  • Secondary (peripheral)
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14
Q

What is the function of primary lymphoid organs?

A

Development and maturation of immunocompetent lymphocytes (into naive lymphocytes)

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15
Q

Examples of primary lymphoid organs

A
  • Fetal liver
  • Bone marrow (pre and postnatal)
  • Thymus
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16
Q

What is the function of secondary (peripheral) lymphoid organs?

A

Proper environment for cells to interact with antigen/other cells

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17
Q

Examples of secondary lymphoid organs

A
  • Diffuse lymphoid tissue
  • Lymph nodes
  • Spleen
  • Postnatal bone marrow
  • Tonsils
18
Q

______ is considered both a primary and secondary lymphoid organ

A

Postnatal bone marrow

19
Q

Which organs are encapsulated in the lymphoid system?

A
  • Thymus
  • Lymph nodes
  • Spleen
  • Tonsils (partially)
20
Q

Two components of the lymphoid system

A
  • Encapsulated organs
  • Diffuse lymphoid tissue
21
Q

Diffuse lymphoid tissue consists of ______

A

Loose conglomerates of lymphoid cells

22
Q

Examples of diffuse lymphoid tissue

A

MALT (GALT and BALT more specifically)

23
Q

What is MALT?

A

Mucosa-associated lymphoid tissue

24
Q

What is GALT?

A

Gut associated lymphoid tissue

25
Q

What is BALT?

A

Bronchus associated lymphoid tissue

26
Q

Which immune cells are derived from the bone marrow?

A
  • T lymphocytes
  • B lymphocytes
  • Macrophages and APCs
27
Q

____ are bone marrow immunocompetent

A

B cells

28
Q

____ are thymus immunocompetent

A

T cells

29
Q

Immunocompetent cells migrate to _____

A

Secondary lymphoid organs

30
Q

Site of T cell maturation

A

Thymus

31
Q

Components of the thymus

A
  • Bilobed
  • Encapsulated organ
32
Q

The thymus is derived from:

A

3rd pharyngeal pouch (possibly fourth as well)

33
Q

What is the function of the thymus?

A
  • Allow immunocompetent and immature T cells to enter
  • T cells mature and enter circulation
34
Q

T cell maturation involves cellular processes such as:

A
  • Formation
  • Potentiation
  • Destruction
35
Q

The thymus arises ____ in embryo

A

Early

36
Q

Thymus is of ____ origin

A

Endodermal

37
Q

The thymus developmental max is ______

A

Shortly after birth

38
Q

What happens to the thymus after puberty?

A
  • Involutes (atrophy)
  • Infiltrated by adipose tissue
  • Cortex diminishes
39
Q

The thymus is surrounded by:

A

CT capsule (dense irregular)

40
Q

In the thymus, there are _____ forming incomplete lobules

A

Septa

41
Q
A

DEN 7101S Human Structure and Function II (21 decks)

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