1F Metabolic Pathways Flashcards

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1
Q

What does an anabolic pathway require?

A

Energy.

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2
Q

What does an anabolic pathway lead to?

A

The synthesis of a molecule.

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3
Q

What does a catabolic pathway release?

A

Energy.

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4
Q

What does a catabolic pathway lead to?

A

The breakdown of a molecule.

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5
Q

Can catabolic and anabolic pathways have steps which are reversible and irreversible?

A

Yes.

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6
Q

What are metabolic pathways controlled by?

A

Enzymes.

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7
Q

Are genes for some enzymes continually expressed?

A

Yes.

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8
Q

Most metabolic pathways are reversible. What can drive the sequence of reactions in a particular direction?

A

The presence of a substrate or the removal of a product.

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9
Q

Describe what is meant by an induced fit.

A

The enzymes active site changes shape to increase the contact between it and the substrate.

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10
Q

What is the roles of the active site

A

Orientate reactants, lower the activation energy of the transition state and the release of products with low affinity for the active side.

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11
Q

What is the effect of increasing enzyme concentration on the rate of a reaction?

A

The rate of the reaction increases until all substrate molecules are being acted upon.

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12
Q

What is the effect of increasing the substrate concentration on the rate of reaction?

A

Increases the rate of reaction until all active sites are accepted by substrate.

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13
Q

Do enzymes act in groups?

A

Yes, often.

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14
Q

Can enzymes act as multi-enzyme complexes?

A

Yes.

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15
Q

What is an inhibitor?

A

A substrate which reduces the rate of reaction.

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16
Q

What is a competitive inhibitor?

A

An inhibitor which had a similar shape to the substrate. It competes for the active site.

17
Q

How does a competitive inhibitor work?

A

It binds to the active site and blocks it so that it cannot act upon the substrate.

18
Q

How does a non-competitor work?

A

By binding to another region on the enzyme which is not the active site (allosteric site).

19
Q

Describe end product inhibition.

A

End product inhibition is brought about by some of the end products of a reaction binding to an enzyme found at the beginning of the metabolic pathway and inhibiting the action of that enzyme.

20
Q

What is the benefit of end-product inhibition?

A

It ensure products do not accumulate and conserved resources.