19. Silicosis Flashcards
what is silicosis
lung fibrosis caused by inhalation of dust containing silica
what is silica, another name and chemical symbol
another name : quartz
SiO2
where is quartz found
earth’s crust, common
all 3 types of rocks
main mineral inside desert sand and beaches
what are some building products that contain silica
concrete, brick
what immune cells attack silica
macrophages
what do macrophages do
engluf and try to dissolve silica crystals
carry silica into lung walls
what forms around dead cells
scar tissues
can continue even after exposure stops
silicosis is a type of …?
pulmonary fibrosis, similar to asbestosis
Scar formation
excess fibrous connective tissue
thickening. of lung walls
less oxygen to blood
shortness of breath
pulmonary fibrosis
progressive
fatal lung disease , only survive 3-5 years
Particles under what size will trap in lungs
10 um less than
what size particles are inhaled into nose or mouth
100um
3 types of ways gaseous things can enter
respirable, thoracic and inhalable
Smallest particles are …
Respirable, particles that go into alveoli, deepest part of lungs
what causes silicosis
crystalline silica exposure
chipping, cutting, drilling, grinding soil or grainite
or disturbing earth’s crust