18. SARS-CoV-2 as an example of a growing virus Flashcards
What’s pandemic
Infection that spreads over a large region of the world in a short amount of time
What is Coronavirus family
Highly diverse family of enveloped positive-sense ssRNA viruses
What’s the main barrier against a jump of a virus from neutral reservoir to a new host
It’s represented by the need for the virus to efficiently recognize and exploit the cellular receptor in the new species
Who helps virus to get in
Angiotensin-converting enzyme 2 and transmembrane protease serine 2
What does substitution rate measures
Pace of mutation accumulation as the virus evolves. It is commonly estimated adopting statistical phylogenetics
What’s crucial fitness element for parasites
Intrinsic ability to transmit