160 heparine

Question 1

Therapeutic classification

Answer 1

Anticoagulant

Question 2

Pharmacologic classification

Answer 2

Indirect thrombin inhibitor

Question 3

Mechanism of action

Answer 3

activates the enzyme antithrombin III, which inhibits thrombin

Question 4

indications

Answer 4

Acute thromboembolic disorders, DVT, Pulmonary embolism, Unstable angina, Evolving MI, Prophylaxis

Question 5

precautions

Answer 5

Peripartum patients, renal or hepatic impairment

Question 6

contraindications

Answer 6

Active internal bleeding, Serious bleeding pathologies, severe HTN, Recent trauma, Intracranial hemorrhage, Bacterial endocarditis, Sulfite sensitivity, Severe thrombocytomenia

Question 7

drug interactions

Answer 7

Potentiated effect with oral anticoagulants; Bleeding with drugs that inhibit platelet aggregation; Inhibited anticoagulation with nicotine, digoxin, tetracyclines, antihistamines; Ginger, garlic, green tea, feverfew, and ginkgo

Question 8

pregnancy category

Answer 8

C

Question 9

adverse effects

Answer 9

Abnormal bleeding, Hemolytic induced thrombocytopenea, mild allergic symptoms, osteoporosis, skin lesions

Question 10

nursing considerations

Answer 10

Complete health history, Baseline blood tests, Monitor aPTT, Collect blood for testing 30 minutes prior to dose, Monitor for signs of bleeding, Apply firm pressure _ 10 minutes for needle sticks, Reduce risk of trauma, Keep heparin antidote readily available

Question 11

Teaching

Answer 11

avoid accident prone activities, report bleeding problems immediately, menstruation may increase, avoid smoking and alcohol, do not take other drugs or supplements, learn subQ injection technique, inform dentist.

Question 12

Antidote

Answer 12

Protamine sulfate

Question 13

Route

Answer 13

IV, Deep subQ