160 Abciximab

Question 1

Therapeutic classification

Answer 1

Antiplatelet agent

Question 2

Pharmacologic classification

Answer 2

Glycoprotien Iib/IIIa inhibitor

Question 3

Mechanism of action

Answer 3

Antibody fragment that binds to glocoprotein Iib/IIIa receptors on platelets, prevents fibrinogen and other procoagulants form activating platelets

Question 4

indications

Answer 4

Acute coronary syndrome, percutaneous coronary intervention

Question 5

precautions

Answer 5

none

Question 6

contraindications

Answer 6

Actie bleeding, recent trauma/surgery, serious bleeding disorders, thrombocytopenia

Question 7

drug interactions

Answer 7

increased risk of bleeding with anticoagulants and thrombolytic agents

Question 8

pregnancy category

Answer 8

C

Question 9

adverse effects

Answer 9

back pain, chest pain, hypotension. Serious adverse effects: abnormal bleeding

Question 10

nursing considerations

Answer 10

Moniter lab tests, observe for bleeding, watch for hypersensitivity, minimize bleeding risk, elevate head of bed and keep limbs straight when femoral artery access is used

Question 11

teaching

Answer 11

immediately report bleeding, do not use other OTC meds or supplements

Question 12

Antidote

Answer 12

none

Question 13

common route

Answer 13

IV