160 Aminocaproic

Question 1

Therapeutic classification

Answer 1

hemostatic/ antifibrinolytic

Question 2

Pharmacologic classification

Answer 2

none

Question 3

Mechanism of action

Answer 3

Occupies binding sites o plasminogen and plasmin, prevents digestion of fibrin clot by plasmin

Question 4

indications

Answer 4

aplastic anemia, hepatic cirrhosis, postoperative cardiac surgery, certain carcinomas, hemophilia A

Question 5

precautions

Answer 5

none

Question 6

contraindications

Answer 6

history of CVA in last 3 months, recent trauma or surgery, active bleeding, severe HTN, intracranial neoplasm, AV malformations

Question 7

drug interactions

Answer 7

antagonizes actioin of thrombolytic agents, hyper coagulation with estrogens and oral contraceptives, increased risk of thrombosis and acute MI with factor IX

Question 8

pregnancy category

Answer 8

C

Question 9

adverse effects

Answer 9

myopathy, hypotension, bradycardia, serious adverse effects: rhabdomyolysis

Question 10

nursing considerations

Answer 10

complete health history, check IV site for extravasatio, nobserve for thrombophlebitis, assess for signs of myopathy

Question 11

teaching

Answer 11

immediately report adverse effects, make position changes slowly, observe for increased toxicity with oral contraceptives and estrogen, immediately notify if pregnant, no breast feed

Question 12

Antidote

Answer 12

none

Question 13

common route

Answer 13

IV