16 - Psychopathology: Biological Basis of Behavioral Disorders Flashcards
Delusion
A false believe strongly held in spite of contrary evidence
Epidemiology
The statistical study of patterns of disease in a population
Schizophrenia
A severe psychopathology characterized by negative symptoms such as emotional withdrawal and impoverished thought, and by positive symptoms such as hallucinations and delusions
Dissociative thinking
A condition, seen in schizophrenia that is characterized by disturbances of thought and difficulty relating events properly
Positive symptom
In psychiatry, an abnormal state. Examples include hallucinations, delusions, and excited motor behavior
Negative symptom
In psychiatry, a symptom that reflects insufficient functioning. Examples include emotional and social withdrawal, blunted affect, and slowness and impoverishment of thought and speech
Monozygotic
Referring to twins derived from a single fertilized egg (identical twins). Such individuals have the same genotype
Dizygotic
Referring to twins derived from separate eggs (fraternal twins). Such twins are no more closely related genetically than are other full siblings
Concordant
Referring to any trait that is seen in both individuals of a pair of twins
Discordant
Referring to any trait that is seen in only one individual of a pair of twins
Hypofrontality hypothesis
The hypothesis that schizophrenia may reflect underactivation of the frontal lobes
Amphetamine psychosis
A delusional and psychotic state, closely resembling acute schizophrenia, that is brought on by repeated use of high doses of amphetamine
Chlorpromazine
An antipsychotic drug, one of the class of phenothiazines
Phenothiazines
A class of antipsychotic drugs that reduce the positive symptoms of schizophrenia
Neuroleptics or antipsychotics
A class of drugs that alleviate symptoms of schizophrenia, typically by blocking dopamine receptors
Typical neuroleptics
A major class of anti-schizophrenic drugs that share an antagonist activity at dopamine D2 receptors
Dopamine hypothesis
The hypothesis that schizophrenia results from excessive levels of synaptic dopamine or excessive postsynaptic sensitivity to dopamine
Dyskinesia
Difficulty or distortion in voluntary movement
Tardive dyskinesia
A disorder characterized by involuntary movements, especially involving the face, mouth, lips, and tongue; related to prolonged use of antipsychotic drugs, such as chlorpromazine
Supersensitivity psychosis
An exaggerated psychosis that may emerge when doses of antipsychotic medication are reduced, probably as a consequence of the up-regulation of receptors that occurred during drug treatment
Atypical neuroleptics
A class of antischizophrenic drugs that have actions other than the dopamine D2 receptor antagonism that characterizes the typical neuroleptics