1.6 proteins Flashcards
What are proteins
Proteins are biological molecules
What are proteins made out of
Amino acids (monomers)
What is the general structure of a protein
An amine group (H2N)
R group
H
Carboxyl group (COOH)
All of which are bonded to a carbon
What type of reactions forms a dipeptide, and what does it mean
Condensation reaction. Water is a result of this type of reaction
What happens in the primary structure of proteins
The sequence of amino acids as determined by genes.
They are joined by peptide bonds
What happens in the secondary structure of proteins. State 2 examples of them.
Folding caused by weak hydrogen bonds (between H, O and N)
- Alpha helix
- Beta sheets (mainly structural e.g keratin & collagen)
What happens in the tertiary structure of proteins. As a result what does this form?
Further folding caused by interactions between different R groups.
Forming:
- Ionic bonds
- Hydrogen bonds
- Disulfide bridges
What is an example of a protein with the tertiary structure
Globular proteins e.g enzymes
What can happen to the bonds in the tertiary structure
The bonds can be broken by changes in pH and an increase of temperature
What happens in the quaternary structure of proteins
Two or more polypeptide chains bonded together
- Some may contain ‘prosthetic groups’
An example: Haemoglobin and antibodies
Where are peptide bonds found (within proteins)
In the primary, secondary and tertiary structure of proteins
Where are hydrogen bonds found (within proteins)
The secondary and tertiary stucture
Where are disulfide bridges and ionic bonds found (within proteins)
In the tertiary structure ONLY