1.5.2 Protozoans (Blood flagellates) Flashcards
American Trypanosomiasis or CHAGAS disease
Trypanosoma cruzi
The transmission of T. cruzi is reduviid bug vector _______ of infective trypomastigotes near the site of its blood meal
Defacation
One of the MOT for T. cruzi includes
Sexual transmission
Transplacental
Eye or mouth mucous membrane when bug bite is near
CSF
Which of the following does not belong
CSF
What is the stage of flagellate in infected person to bug?
Trypomastigote
What is the stage of flagellate in Diagnostic stage for humans?
Trypomastigote
Stage of flagellate once trypomastigote enters the tissue?
Amastigote
Vectors of T. cruzi includes:
Reduvlid bug
Kissing bug
Assassin bug
Traitome bug
Conenose bug
Which of the following does not belong?
None
Reservoir for T. cruzi includes:
mammalian
Dogs
cats
T or F
T
Most common Initial symptoms of T. cruzi?
Chagoma
This is an erythematous nodule at the site of an infection due to parasite proliferation
Chagoma
Chagoma is present anywhere on the body, most frequently on the _______?
Face
Contraction through ocular mucoa leads to unilateral ophthalmia with edema, conjunctivitis, swell of lyph nodes
Romana sign
Romana sign
a. Trypanosoma cruzi
b. Trypanosoma brucei gambience
c. Trypanosoma rhodesience
a
Chronic Trypanosomiasis (MEGAcolon, megaesophagus, cardiomyopathy, cardiomegaly)
a. Trypanosoma cruzi
b. Trypanosoma brucei gambience
c. Trypanosoma rhodesience
a
ANYTHING THAT ENLARGES
WEST African Sleeping sickness, Gambian trypanosomiasis
a. Trypanosoma cruzi
b. Trypanosoma brucei gambience
c. Trypanosoma rhodesience
b
T. brucei gamibience is MORE aggressive than that of its East African counterpart
T or F
F
Less
The incubation for T. brucei gambience is few days to several weeks
T or F
T
Causes painful chancre (ulcer) which surrounded by a white halo at the bite
a. Trypanosoma cruzi
b. Trypanosoma brucei gambience
c. Trypanosoma rhodesience
b
A condition known as ___________ sign refers to the enlargement of the cervical lymph nodes in reference to this trypanosomal disease
Winter bottom
Winter bottom (Lymphadenopathy)
a. Trypanosoma cruzi
b. Trypanosoma brucei gambience
c. Trypanosoma rhodesience
b
Winter bottom blocks/delays the parasite from entering the brain making less virulent than T. brucei rhodesiense
T or F
T
Kerandal sign is a delay sensation to?
PAin
Final stage of T. brucei gambience is coma and death coupled with pneumonia or malaria
T or F
T
EAST african sleeping sickness, Rhodesian trypanosomiasis
a. Trypanosoma cruzi
b. Trypanosoma brucei gambience
c. Trypanosoma rhodesience
c
More FATAL
a. Trypanosoma cruzi
b. Trypanosoma brucei gambience
c. Trypanosoma brucei rhodesience
c
Vector for T. brucei rhodesience?
Glossina/Tsetse fly
Reservoir for T. brucei rhodesience?
Cattle and Sheep
East African sleeping sickness is more virulent than T.b. gambiance?
T or F
T
Incubation of T.b. rhodesience
Short
Winterbottom sign for T.b. rhodesience
pos or neg?
Mostly neg but may pos
Lymphadenopathy presesnt in T.b rhodesience
T or F
F
CNS involvement involve earlier in T.b gambience than rhodesience
T or F
F
T.b rhodesience is more earlier because their is no Winterbottom’s sign that can delay this parasite
Rapid weight loss is caused by
a. Trypanosoma cruzi
b. Trypanosoma brucei gambience
c. Trypanosoma rhodesience
c
A rapid and fulminating disease results, with small numbers of trypanosomes circulating in the blood
T or F
F
Large
T.b rhodesience
Death, in part caused by subsequent _______ damage and myocarditis usually occurs within __________ in untreated patient
Kidney, 9-12 months
Stain for T. cruzi
Giemsa stain
Epimastigote is usually seen in?
Arthropod / Insect
Amastigote is seen in what specime?
What is the stain used?
Lymph node biopsy,
Giemsa stain
Traditional method for diagnosis of T. cruzi?
Xenodiagnosis
Infected patient + uninfected bug
Treatment of choice for T. cruzi
Nifurtimox (Lampit)
SOC for T.b gambience includes:
Blood
Lymph nodes aspiration
CSF
Serum
Which of the following does not belong?
Serum
Stain for T.b gambience?
Giemsa
What is being detected in Giemsa stain?
Trypomastigote
IgM positive is a diagnosis in serology for T.b ambiance
T or F
T
SOC for T.b rhodesience is blood slide stained with Giemsa stain and microscopic examination of _________ sediment
CSF
In T.b. rhodesience, the presence of _________ in CSF is a diagnosis for it
IgM
