1.5.2 Protozoans (Blood flagellates)

Question 1

American Trypanosomiasis or CHAGAS disease

Answer 1

Trypanosoma cruzi

Question 2

The transmission of T. cruzi is reduviid bug vector _______ of infective trypomastigotes near the site of its blood meal

Answer 2

Defacation

Question 3

One of the MOT for T. cruzi includes

Sexual transmission
Transplacental

Eye or mouth mucous membrane when bug bite is near

CSF

Which of the following does not belong

Answer 3

CSF

Question 4

What is the stage of flagellate in infected person to bug?

Answer 4

Trypomastigote

Question 5

What is the stage of flagellate in Diagnostic stage for humans?

Answer 5

Trypomastigote

Question 6

Stage of flagellate once trypomastigote enters the tissue?

Answer 6

Amastigote

Question 7

Vectors of T. cruzi includes:

Reduvlid bug
Kissing bug
Assassin bug
Traitome bug
Conenose bug

Which of the following does not belong?

Answer 7

None

Question 8

Reservoir for T. cruzi includes:

mammalian
Dogs
cats

T or F

Answer 8

T

Question 9

Most common Initial symptoms of T. cruzi?

Answer 9

Chagoma

Question 10

This is an erythematous nodule at the site of an infection due to parasite proliferation

Answer 10

Chagoma

Question 11

Chagoma is present anywhere on the body, most frequently on the _______?

Answer 11

Face

Question 12

Contraction through ocular mucoa leads to unilateral ophthalmia with edema, conjunctivitis, swell of lyph nodes

Answer 12

Romana sign

Question 13

Romana sign

a. Trypanosoma cruzi
b. Trypanosoma brucei gambience
c. Trypanosoma rhodesience

Answer 13

a

Question 14

Chronic Trypanosomiasis (MEGAcolon, megaesophagus, cardiomyopathy, cardiomegaly)

a. Trypanosoma cruzi
b. Trypanosoma brucei gambience
c. Trypanosoma rhodesience

Answer 14

a

ANYTHING THAT ENLARGES

Question 15

WEST African Sleeping sickness, Gambian trypanosomiasis

a. Trypanosoma cruzi
b. Trypanosoma brucei gambience
c. Trypanosoma rhodesience

Answer 15

b

Question 16

T. brucei gamibience is MORE aggressive than that of its East African counterpart

T or F

Answer 16

F

Less

Question 17

The incubation for T. brucei gambience is few days to several weeks

T or F

Answer 17

T

Question 18

Causes painful chancre (ulcer) which surrounded by a white halo at the bite

a. Trypanosoma cruzi
b. Trypanosoma brucei gambience
c. Trypanosoma rhodesience

Answer 18

b

Question 19

A condition known as ___________ sign refers to the enlargement of the cervical lymph nodes in reference to this trypanosomal disease

Answer 19

Winter bottom

Question 20

Winter bottom (Lymphadenopathy)

a. Trypanosoma cruzi
b. Trypanosoma brucei gambience
c. Trypanosoma rhodesience

Answer 20

b

Question 21

Winter bottom blocks/delays the parasite from entering the brain making less virulent than T. brucei rhodesiense

T or F

Answer 21

T

Question 22

Kerandal sign is a delay sensation to?

Answer 22

PAin

Question 23

Final stage of T. brucei gambience is coma and death coupled with pneumonia or malaria

T or F

Answer 23

T

Question 24

EAST african sleeping sickness, Rhodesian trypanosomiasis

a. Trypanosoma cruzi
b. Trypanosoma brucei gambience
c. Trypanosoma rhodesience

Answer 24

c

Question 25

More FATAL a. Trypanosoma cruzi b. Trypanosoma brucei gambience c. Trypanosoma brucei rhodesience

Answer 25

c

Question 26

Vector for T. brucei rhodesience?

Answer 26

Glossina/Tsetse fly

Question 27

Reservoir for T. brucei rhodesience?

Answer 27

Cattle and Sheep

Question 28

East African sleeping sickness is more virulent than T.b. gambiance? T or F

Answer 28

T

Question 29

Incubation of T.b. rhodesience

Answer 29

Short

Question 30

Winterbottom sign for T.b. rhodesience pos or neg?

Answer 30

Mostly neg but may pos

Question 31

Lymphadenopathy presesnt in T.b rhodesience T or F

Answer 31

F

Question 32

CNS involvement involve earlier in T.b gambience than rhodesience T or F

Answer 32

F T.b rhodesience is more earlier because their is no Winterbottom's sign that can delay this parasite

Question 33

Rapid weight loss is caused by a. Trypanosoma cruzi b. Trypanosoma brucei gambience c. Trypanosoma rhodesience

Answer 33

c

Question 34

A rapid and fulminating disease results, with small numbers of trypanosomes circulating in the blood T or F

Answer 34

F Large

Question 35

T.b rhodesience Death, in part caused by subsequent _______ damage and myocarditis usually occurs within __________ in untreated patient

Answer 35

Kidney, 9-12 months

Question 36

Stain for T. cruzi

Answer 36

Giemsa stain

Question 37

Epimastigote is usually seen in?

Answer 37

Arthropod / Insect

Question 38

Amastigote is seen in what specime? What is the stain used?

Answer 38

Lymph node biopsy, Giemsa stain

Question 39

Traditional method for diagnosis of T. cruzi?

Answer 39

Xenodiagnosis Infected patient + uninfected bug

Question 40

Treatment of choice for T. cruzi

Answer 40

Nifurtimox (Lampit)

Question 41

SOC for T.b gambience includes: Blood Lymph nodes aspiration CSF Serum Which of the following does not belong?

Answer 41

Serum

Question 42

Stain for T.b gambience?

Answer 42

Giemsa

Question 43

What is being detected in Giemsa stain?

Answer 43

Trypomastigote

Question 44

IgM positive is a diagnosis in serology for T.b ambiance T or F

Answer 44

T

Question 45

SOC for T.b rhodesience is blood slide stained with Giemsa stain and microscopic examination of _________ sediment

Answer 45

CSF

Question 46

In T.b. rhodesience, the presence of _________ in CSF is a diagnosis for it

Answer 46

IgM