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MTAP 1 Para > 1.5.2 Protozoans (Blood flagellates) > Flashcards

1.5.2 Protozoans (Blood flagellates) Flashcards

1
Q

American Trypanosomiasis or CHAGAS disease

A

Trypanosoma cruzi

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2
Q

The transmission of T. cruzi is reduviid bug vector _______ of infective trypomastigotes near the site of its blood meal

A

Defacation

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3
Q

One of the MOT for T. cruzi includes

Sexual transmission
Transplacental

Eye or mouth mucous membrane when bug bite is near

CSF

Which of the following does not belong

A

CSF

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4
Q

What is the stage of flagellate in infected person to bug?

A

Trypomastigote

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5
Q

What is the stage of flagellate in Diagnostic stage for humans?

A

Trypomastigote

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6
Q

Stage of flagellate once trypomastigote enters the tissue?

A

Amastigote

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7
Q

Vectors of T. cruzi includes:

Reduvlid bug
Kissing bug
Assassin bug
Traitome bug
Conenose bug

Which of the following does not belong?

A

None

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8
Q

Reservoir for T. cruzi includes:

mammalian
Dogs
cats

T or F

A

T

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9
Q

Most common Initial symptoms of T. cruzi?

A

Chagoma

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10
Q

This is an erythematous nodule at the site of an infection due to parasite proliferation

A

Chagoma

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11
Q

Chagoma is present anywhere on the body, most frequently on the _______?

A

Face

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12
Q

Contraction through ocular mucoa leads to unilateral ophthalmia with edema, conjunctivitis, swell of lyph nodes

A

Romana sign

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13
Q

Romana sign

a. Trypanosoma cruzi
b. Trypanosoma brucei gambience
c. Trypanosoma rhodesience

A

a

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14
Q

Chronic Trypanosomiasis (MEGAcolon, megaesophagus, cardiomyopathy, cardiomegaly)

a. Trypanosoma cruzi
b. Trypanosoma brucei gambience
c. Trypanosoma rhodesience

A

a

ANYTHING THAT ENLARGES

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15
Q

WEST African Sleeping sickness, Gambian trypanosomiasis

a. Trypanosoma cruzi
b. Trypanosoma brucei gambience
c. Trypanosoma rhodesience

A

b

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16
Q

T. brucei gamibience is MORE aggressive than that of its East African counterpart

T or F

A

F

Less

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17
Q

The incubation for T. brucei gambience is few days to several weeks

T or F

A

T

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18
Q

Causes painful chancre (ulcer) which surrounded by a white halo at the bite

a. Trypanosoma cruzi
b. Trypanosoma brucei gambience
c. Trypanosoma rhodesience

A

b

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19
Q

A condition known as ___________ sign refers to the enlargement of the cervical lymph nodes in reference to this trypanosomal disease

A

Winter bottom

20
Q

Winter bottom (Lymphadenopathy)

a. Trypanosoma cruzi
b. Trypanosoma brucei gambience
c. Trypanosoma rhodesience

A

b

21
Q

Winter bottom blocks/delays the parasite from entering the brain making less virulent than T. brucei rhodesiense

T or F

A

T

22
Q

Kerandal sign is a delay sensation to?

A

PAin

23
Q

Final stage of T. brucei gambience is coma and death coupled with pneumonia or malaria

T or F

A

T

24
Q

EAST african sleeping sickness, Rhodesian trypanosomiasis

a. Trypanosoma cruzi
b. Trypanosoma brucei gambience
c. Trypanosoma rhodesience

A

c

25
Q

More FATAL

a. Trypanosoma cruzi
b. Trypanosoma brucei gambience
c. Trypanosoma brucei rhodesience

A

c

26
Q

Vector for T. brucei rhodesience?

A

Glossina/Tsetse fly

27
Q

Reservoir for T. brucei rhodesience?

A

Cattle and Sheep

28
Q

East African sleeping sickness is more virulent than T.b. gambiance?

T or F

A

T

29
Q

Incubation of T.b. rhodesience

A

Short

30
Q

Winterbottom sign for T.b. rhodesience

pos or neg?

A

Mostly neg but may pos

31
Q

Lymphadenopathy presesnt in T.b rhodesience

T or F

A

F

32
Q

CNS involvement involve earlier in T.b gambience than rhodesience

T or F

A

F

T.b rhodesience is more earlier because their is no Winterbottom’s sign that can delay this parasite

33
Q

Rapid weight loss is caused by

a. Trypanosoma cruzi
b. Trypanosoma brucei gambience
c. Trypanosoma rhodesience

A

c

34
Q

A rapid and fulminating disease results, with small numbers of trypanosomes circulating in the blood

T or F

A

F

Large

35
Q

T.b rhodesience

Death, in part caused by subsequent _______ damage and myocarditis usually occurs within __________ in untreated patient

A

Kidney, 9-12 months

36
Q

Stain for T. cruzi

A

Giemsa stain

37
Q

Epimastigote is usually seen in?

A

Arthropod / Insect

38
Q

Amastigote is seen in what specime?

What is the stain used?

A

Lymph node biopsy,

Giemsa stain

39
Q

Traditional method for diagnosis of T. cruzi?

A

Xenodiagnosis

Infected patient + uninfected bug

40
Q

Treatment of choice for T. cruzi

A

Nifurtimox (Lampit)

41
Q

SOC for T.b gambience includes:

Blood
Lymph nodes aspiration
CSF
Serum

Which of the following does not belong?

A

Serum

42
Q

Stain for T.b gambience?

A

Giemsa

43
Q

What is being detected in Giemsa stain?

A

Trypomastigote

44
Q

IgM positive is a diagnosis in serology for T.b ambiance

T or F

A

T

45
Q

SOC for T.b rhodesience is blood slide stained with Giemsa stain and microscopic examination of _________ sediment

A

CSF

46
Q

In T.b. rhodesience, the presence of _________ in CSF is a diagnosis for it

A

IgM

MTAP 1 Para (21 decks)

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