1.5 - Proteins and Nucleic Acids Flashcards

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1
Q

Tell me about Proteins

A

Proteins account for more than 50% of the dry weight of most cells and are involved in almost everything the cell does.

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2
Q

what are proteins made of

A

They are made of long chains of amino acids that fold around each other due to intra and inter-molecular forces.

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3
Q

the 7 classes/functions of proteins

A

Structural Proteins, Contractile Proteins, Storage Proteins, Defensive Proteins, Transport Proteins, Enzyme Proteins, Hormonal Proteins

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4
Q

Structural Proteins

A

Functions in the cell membrane and muscle tissue. It makes up animal hair, spider silk, and our tendons and ligaments.

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5
Q

Contractile Proteins

A

Works with structural proteins. Provides muscle movement.

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6
Q

Storage Proteins

A

Albumin (egg white) serves as the source of amino acids for developing embryos. (they are storage)

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7
Q

Defensive Proteins

A

Carries antibodies that fight infection. They are carried in the blood.

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8
Q

Transport Proteins

A

Includes hemoglobin (the iron containing protein in the blood that transports oxygen from the lungs to the rest of the body)

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9
Q

Enzyme Proteins

A

Most important. Enzyme proteins promote and regulate all chemical reactions in the cells.

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10
Q

Hormone Proteins

A

Hormone proteins such as insulin act as chemical messengers in cells and in the extracellular environment

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11
Q

Amino acids

A

Amino acids can be polar, non-polar, or charged (acidic or basic) and determine the biological activity of protein.

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12
Q

Peptides

A

Peptides are short strings of AA, typically comprising 2–50 amino acids.

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13
Q

how long can protein be

A

Protein length can range from 8-2000 AA (amino acids) long.

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14
Q

1 AA=
2 AAs=
Many AAs=
1 or more polypeptide chains=

A

1 AA = 1 AA monomer
2 AAs = a dipeptide molecule
Many AAs = a polypeptide chain
1 or more polypeptide chains = a protein molecule

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15
Q

The 4 Protein Structures.

A

Primary Protein Structure
Secondary Protein Structure
Tertiary Protein Structure
Quaternary Protein Structure

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16
Q

Primary Protein Structure

A

Primary Protein structure is a sequence of amino acids (looks like a chain)

17
Q

Secondary Protein Structure

A

Secondary Protein Structures are when H bonds between AA make α-helices and β-pleated sheets (α looks like a helix, β looks like semi folded sheet metal)

18
Q

Tertiary Protein Structure

A

Tertiary Protein Structure are further folds of polypeptides (Secondary) stabilized by functional group interactions (looks like a group of the 1st and 2nd Protein Structure)

19
Q

Quaternary Protein Structure

A

clustering of 2+ polypeptides in

tertiary structure

20
Q

Fibrous Protein Structure

A

Strong, linear in shape (due to

parallel polypeptide chains and Beta pleated sheets), Insoluble in water, Ex: collagen, silk, keratin

21
Q

Globular Protein Structure

A

Spherical in shape, have a hydrophobic group on
the inside, have a hydrophilic group on
the outside, soluble in water, Ex: enzymes, antibodies, hormones

22
Q

Denatured Protein

A

Denatured proteins cannot carry out their functions and are caused by chemicals or heat disrupting the H-Bonds, Ionic Bonds, DiSulfide Bridges, and Hydrophobic interactions

23
Q

Nucleic acids

A

Nucleic acids are polymers formed from nucleotides. Each nucleotide contains a nitrogenous base, a 5 carbon pentose sugar, and a phosphate group

24
Q

Nucleotides Sugar Groups

A

Nucleotides all contain sugar groups which either contain Deoxyribose (DNA) or Ribose (RNA)

25
Q

2 Nitrogenous Base Groups

A

Pyrimidines (one ring) or Purines (two rings)

26
Q

DNA

A

Deoxyribonucleic acid
A polymer
The genetic code for all proteins and life functions
2 nucleotide strands linked by hydrogen bonds
between nitrogenous bases (A&T, C&G
Has a double helix structure
Unique genetic information is determined by the
sequence of nucleotides

27
Q

RNA

A

Ribonucleic Acid
A polymer
A template of 1 gene, a code for 1 protein
RNA carries the protein “blueprint”, copied from DNA, from the nucleus to the cytoplasm, where a ribosome assembles the proper protein sequence
Contains A&U, C&G
mRNA and tRNA