1.5 Programmed Cell Death; Apoptosis

Question 1

What triggers apoptosis

Answer 1

Internal or external cell death signals

Question 2

What is apoptosis

Answer 2

The death of cells which occurs as a normal and controlled part of an organisms growth/development
(Programmed cell death)

Question 3

Give an example of an extrinsic death signal

Answer 3

Cell death signal molecules from lymphocytes

Question 4

How do extrinsic death signals work

Answer 4

The death signal molecules bind to a surface receptor protein and trigger a protein cascade within the cytoplasm

Question 5

Give an sample of an intrinsic death signal

Answer 5

DNA damage

Question 6

What does an internal death signal from DNA damage cause

Answer 6

The activation of p53 tumor supressor protein

Question 7

Both types of cell death signals activate ….. that cause the…..

Answer 7

Caspases, the destruction of the cell

Question 8

Apoptosis is essential in the development of an organism to…

Answer 8

Remove cells no longer required as development progresses
During metamorphosis
Eg tadpole tail is lost in metamorphosis via apoptosis