1.3 Membrane Proteins Flashcards
Integral membrane proteins are found …
In the phospholipid bilayer
Integral membrane proteins have extensive interactions with
The hydrophobic region of membrane phospholipids
Integral: regions of hydrophobic R groups allow
Strong hydrophobic interactions that hold integral membrane proteins within the phospholipid bilayer
Some integral membranes are transmembrane proteins this means:
They span the entirety of the cell membrane
What do many peripheral membrane proteins interact with
The surfaces of integral membrane proteins
What type of R groups do peripheral membrane proteins have on their surface
Hydrophilic
Peripheral membrane proteins are bound to the surface of membranes by
Mainly ionic and hydrogen bond interactions
The phospholipid bilayer is a barrier to:
Ions and most uncharged polar molecules
CO2 and oxygen can pass through the phospholipid bilayer via
Diffusion
Define facilitated diffusion
The passive transport of substances across a membrane through specific transmembrane proteins
What are the two channel types
Ligand gated channel, voltage gated channel
Describe a channel
A multi subunit protein with the subunits arranged to form water filled pores that extent across the membrane
What are ligand gated channels controlled by
The binding of signal molecules
What are voltage gated channels controlled by
The changes in ion concentration
Describe pump proteins
Activate transport transfers substances across the membrane against their concentration gradient
Transporter proteins coupled to an energy source