1.2 Protein Structure

Question 1

Describe primary protein structure

Answer 1

The sequence in which amino acids are synthesized into the polypeptide

Question 2

Define secondary protein structure

Answer 2

Local folding of the polypeptide chain into alpha helices, beta pleated sheets, turns

Question 3

What are the features of secondary protein structure

Answer 3

Alpha helices, beta pleated sheets, turns

Question 4

What causes secondary protein structure

Answer 4

Hydrogen bonding along the backbone of the protein strand

Question 5

Describe tertiary protein structure

Answer 5

Three dimensional folding pattern of the protein

Question 6

What stabilizes tertiary protein structure

Answer 6

Interactions between R groups
Eg hydrophobic interactions, iconic bonds, London dispersion forces, hydrogen bonds, disulfide bridges

Question 7

Describe quaternary protein structure

Answer 7

Proteins with two or more connected polypeptide subunits

Question 8

What is a prosthetic group

Answer 8

A non protein unit, tightly bound to a protein and necessary to its function

Question 9

Give an example of a prosthetic group

Answer 9

Haem group in haemoglobin
It’s presence allows haemoglobin to bind to oxygen