1.5 Intro to Pharm Flashcards

1
Q

Drug

A

any chemical agent that in small quantities affects the processes of human beings

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2
Q

curative

A

cures the disease

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3
Q

pallative

A

manages symptoms

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4
Q

3 physical characteristics of a drug

A
  1. form (solid? liquid? pill?)
  2. Ionization based on pKa
  3. how does it move in the body
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5
Q

_______ pKa = stronger acid

A

low

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6
Q

inflammation ________ pH

A

lowers

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7
Q

Enantiomers have the same chemical properties but act different if?

A

they are in a stereoselective environment

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8
Q

The body likes ____ Amino acids and ____ sugars

A

L, D

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9
Q

receptor

A

molecule structure or site on the surface or interior of a cell that binds with substances such as hormones, antigens, drugs or neurotransmitters and initiates the biochemical events leading to a physiological response

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10
Q

receptors can be in which 3 places?

A
  1. surface mem
  2. cytoplasm
  3. nucleus
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11
Q

Pharmacodynamics

A

what the DRUG does to the body

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12
Q

pharmacokinetics

A

what the BODY does to the drug

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13
Q

pharmacogenomics

A

testing of genetic variation that gives rise to different responses to drugs

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14
Q

pharmacotheraputics

A

drugs in the prevention and treatment of disease

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15
Q

toxicology

A

study of poisons

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16
Q

pharmacognosy

A

study of chemistry, activity and use of natural compounds

17
Q

pharmacovigilance

A

surveillance of adverse effects and drug interaction

18
Q

you must prove what 2 things to the FDA?

A

safety

efficacy

19
Q

Clinical trials have _____ phases. what are they?

A

3: is it safe, does it work to patients, does it work double blind