13.7 Gestational Pathology Flashcards
What is the MC site of ectopic pregnancy
fallopian tube
what is key risk factor for ectopic pregnancy?
scarring
What 2 conditions usually lead to scarring that causes ectopic pregnancy
pelvic inflammatory disease
endometriosis
Where is pain of ectopic pregnancy usually present
lower quadrant abdominal pain
two major complications of ectopic pregnancy
hematosalpinx- bleeding into fallopian tube
rupture of “ “
define spontaneous abortion
miscarriage before 20 weeks(1st trimester)
frequency of spontaneous abortion
1/4 pregnancies
MC cause of spontaneous abortion
chromosomal abnormalities (trisomy 16 usually)
3 causes of spontaneous abortion other than chromosomal abnormality
hypercoagulable states (SLE)
congenital infection
teratogens
effect of teratogen exposure in first 2 weeks
spontaneous abortion
effect of teratogen exposure weeks 3-8
organ malfunciton
effect of teratogen exposure months 3-9
organ hypoplasia
Define placenta previa`
placenta covers cervical os
placenta previa` presents as what, when?
3rd trimester bleeding
tx for placenta previa`
C-section
define placental abruption
separation of placenta from decidua prior to delivery
what is placental abruption a comon cause of
still birth
placental abruption presents with what 2, when?
fetal insufficiency (no oxygen to fetus) bleeding in 3rd trimester
define placenta accreta
improper implantation of placenta into myometrium (with little or no decidua)
how does placenta accreta present (2)
delivery of placenta
postpartum bleeding
tx for placenta accreta?
often requires hysterectomy
cocaine leads to what 2 fetal effects
intrauterine growth retardation, placental abruption (dt vasoconstriction)
Alcohol leads to what 3 fetal effects
mental retardation
microcephaly
facial abnormalities
Thalidomide leads to whatfetal effect
limb defects