Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pathoma 13. Female Genital System and Gestational Pathology > 13.2 Vagina > Flashcards

13.2 Vagina Flashcards

1
Q

what epithelium is the vagina lined by

A

nono-keratinized squamous

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Define Adenosis

A

focal persistence of columnar epithelium in the upper vagina

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is lower 1/3rd of vagina derived from

A

Urogenital Sinus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is yupper 2/3rds of vagina derived from

A

Mullerian ducts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

As fetus what is lower and upper vagina lined by respectively?

A

upper = columnar

lower- stratified squamous epithelium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What causes Adenosis

A

mothers exposed to DES (diethylstibestrol) in utero

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What does Adenosis progress to sometimes?

A

Clear cell adenocarcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

define Adenocarcinoma

A

malignant proliferation of glands with clear cytoplasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what is adenocarcinoma a complication of?

A

DES-asociated vaginal adenosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what are the other complications of DES usage (2)

A

smooth muscle abnormalities–> uterine abnormalities–> ectopic pregnancies
Mother has increased risk for Breast Carcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

define Embryonal Rhbdomyosarcoma

A

malignant mesenchymal proliferation of immature skeletal muscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

How does Embryonal Rhbdomyosarcoma present

A

grape-like mass proteuding from vagina or penis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What population MC has Embryonal Rhbdomyosarcoma

A

<5 yo girls

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what is the chc cell of Embryonal Rhbdomyosarcoma

A

Rhabdomyoblast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What does a Rhabdomyoblast exhibit in cytoplasm?

A

cross-striations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What 2 substances will a Rhabdomyoblast stain positive for?

A

desmin, myogenin

17
Q

what is desmin

A

intermediate filament in muscle cells

18
Q

what is myogenin

A

nuclear TF present in immature Skeletal muscle

19
Q

What does vaginal carcinoma arise from

A

squamous epithelium of vagina

20
Q

what is vaginal carcinoma related to

A

high risk HPV (16, 18, 31, 33)

21
Q

What is the precursor lesion to vaginal carcinoma

A

Vaginal intraepithelial neoplasia (VAIN)

22
Q

cancers from the lower 1/3 of the vagina drain to which LNs?

A

inguinal LNs

23
Q

cancers from the Upper 2/3 of the vagina drain to which LNs?

A

regional iliac LNs

Pathoma 13. Female Genital System and Gestational Pathology (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions