1.3 Malignant Scrotal Pathologies Flashcards
Malignant Testicular tumors often present with (7)
painless Scrotal enlargement Hardness of testicle Unilateral hypoechoic Increased vascularity May have hydrocele?
Malignant Tumors most common cause of death in men between age ___ to ___
15-34
Malignant tumors arise from?
Germ cells
What are the 2 types of germ cell tumors (not L & S)
Seminomas and Nonsemionmatous tumors
WHAT IS THE MOST COMMON TYPE OF GERM CELL TUMOR?
SEMINOMAS
Seminomas often occur in men __ to __ years
30-40
What blood work is seen with Seminomas
Increase____ normal_____
BETA HCG ; AFP
What are the least aggressive malignant tumors with best prognosis?
seminomas
What is the sonographic appearance of a seminoma? (5)
Solid Homogenous Hypoechoic Scattered hyperechoic areas (like micro calcs) pseudocapsule
What is the more aggresssive tumor than seminoma tumors?
non seminomatous germ cell tumors
NSGCT
non seminomatous germ cell tumors (NSGCT) cause _________ meaning they spread to other organs
Visceral Matastases
non seminomatous germ cell tumors (NSGCT) Include which tumors?
Embryonal cell carcinoma Yolk Sac tumor Coriocarcinoma Teratoma Mixed germ cell tumors
What is the 2nd most common type of testicular cancer
remember: seminoma 1st- way more common
Embryonal Cell Carcinoma
Embryonal Cell Carcinoma tends to occur in men ___ to ___ years
25-35
The most aggressive testicular cancer is ?
Embryonal Cell Carcinoma
WHAT BLOOD WORK MAY OR MAY NOT BE ELEVATED IN THESE PATIENTS WITH EMBRYONAL CELL?
AFP
what is the most common infantile (< 2yrs) form of embryonal cell carcinoma?
yolk sac tumor
What blood work is always elevated with yolk sac tumor?
AFP
What is the sonographic appearance of embryonal cell carcinomas (3)
Hypoechoic
often mixed echogenicity
more poorly defined then seminoma
What is an uncommon agressive tumor affecting 20 - 30 years of age
Coriocarcinoma
Coriocarcinoma has high incidence of ______ involvement
pulmonary
may metastasize to lungs
WHAT BLOOD WORK IS ALWAYS ELEVATED IN Coriocarcinoma
SERUM BETA HCG
bc of this may cause gynecomastica/scrotal pain
Coriocarcinoma sonographically
small, mixed echogenicity, irregular boarders
Teratoma (rare) occur at low frequency and typically____ in children and ____ in adults
Benign; malignant
WHAT BLOOD MAYBE ELEVATED IN Teratoma suggesting malignancy?
AFP &; BETA HCG
Teratoma Sonographically
Cysitc and Solid components
May demonstrate, shadow or enhancement
well defined
What is the most common Mixed Germ cell Tumor
Teratocarcinoma (teratoma mixed with Embryonal cell)
What is the largest malignant tumor?
Mixed Germ cell Tumor
Mixed Germ cell Tumor sonographically
Large
Heterogenous
Cystic areas and echogenic foci
How do you differentiate testicular tumors
Biopsy
What is a burned out tumor?
Echogenic or calcified scar in the testicle. Regression of a primary tumors (outgrows its blood supply and regresses)
REVIEW QUESTIONS
…………..
what is metastatic disease
Cancer originated else where (another primary site) and has spread to the testicular tissue
What is the most common metastatic tumor of the testes ?
Lymphoma
Lymphoma is most common in what age group?
> 50 years old
What is the mot common TYPE of Lymphoma
Non-Hodgkin
What is the most common presentation of Lymphoma
Painless
mass
DIFFUSE enlargement
Metastatic Lymphoma sonographically (4)
Hypo
homogenous
DIFFUSE (entire teste enlarged) or focal mass
Hypervascular
What is the SECOND most common metastatic tumor of the testes ?
Leukemia
What is the most common NON-lymphamatous metastatic tumor of the testes ?
Prostate & lung
Metastatic Spread possible routes (4)
Retrograde venous
Hematogenous (arterial supply)
Retrograde lymphatic system
or direct tumor invasion
Post Vascectomy changes occur in ____ % patients
45
Vasectomy changes include (5)
Epididymal enlargement Heterogenous Cysts/ Spermatoceles Sperm Granuloma (sperm escapes and is walled off) Tubular Ectasia
What is Tubular Ectasia
dilated tubules in epi or Rete testes
Various sized cystic lesions maybe mistaken for neoplasm
bilateral but asymmetrical
often has a spermatocele
Tubular Ectasia will not demonstrate?
COLOR FLOW
unlike varicocele in testicles that will have flow
Ultrasound after a Post Orchiectomy can be use to assess (4)
assess the scrotal space for
- Abscess
- Hematoma
- Recurrent neoplasms
- or for placement of Prosthesis
MORE REVIEW
MOST COMMON CAUSE OF PAINLESS SCROTAL SWELLING
Hydrocele (collection of fluid in bw layers of tunica vag)
WHAT IS THE STRUCTURE THAT FORMS THE MEDIASTINUM?
TUNICA ALBUGINEA (supportive structure for RT)
WHAT OTHER EPIDIDYMAL ABNORMALITY CAN TYPICAL OCCUR WITH TUBUALR ECTASIA?
Spermatocele
WHAT IS THE MOST COMMON TYPE OF TESTICULAR TORSION?
Intravaginal (associated -bell clapper)
MOST COMMON CAUSE OF ACUTE SCROTAL PAIN
Epididymitis
WHAT IS THE ALTERNATIVE NAME FOR THE EPI HEAD
Globus major