13 Gall Bladder Disorders Flashcards
Cholelithiasis
Presence of gall stones within gall bladder or biliary duct system
Cholecystitis
Inflammation of gall bladder, usually by obstruction of cystic duct by gall stone
Type of gall stone
Cholesterol stone
Pigment stone
Pathophysiology of cholithiasis
- Abnormal bile composition
- excessive cholesterol in bile due to obesity, high calories and cholesterol diet
- bile supersaturated with Cholesterol, precipitate to form stones - Biliary stasis
Slow emptying, contribute to stone formation - Inflammation of gall bladder
Excessive water and ball salt reabsorption, increase risk of stone formation
Migrate into duct, cholangitis
Cholangitis膽管炎
What happen if obstruction in common bile duct
bile reflux to liver
Liver damage, jaundice, pain
Why rapid weight loss cause cholelithiasis
Increase cholesterol concentration in bile and decrease gallbladder contraction
Which kind of drug increase risk of cholelithiasis
Oral contraceptive
Increase cholesterol levels
Biliary colic location
RUQ
Cholelithiasis: why epigestric fullness, distress and pain after heavy meal
Bile secretion and contraction increase
Move stone
How cholecystitis cause peritonitis
Obstruction of cystic duct by stone
Increase pressure within gallbladder
Ischemia of gallbladder wall & mucosa
Necrosis and perforation
Empyema
Collection of infected fluid
積膿
Manifestation of cholecystitis
Acute pain (RUQ, radiate to back shoulder and right scapula, aggregate by movement)
RUQ tenderness to palpation
Restlessness, diaphoresis, n/
Chills
Diaphoresis
Excessive sweating
Why diagnosis
Serum bilirubin
amylase and lipase
CBC
Serum bilirubin: any obstruction of duct
amylase and lipase: pancreatitis
CBC: inflammation (WBC)