10.1 Liver cirrhosis Flashcards

1
Q

Two main blood supply of liver

A

Portal vein
Hepatic artery

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2
Q

Function of liver

A

Ammonia conversion
Bile formation
Bilirubin excretion
Cholesterol synthesis
Detoxification
Emulsification of fats
Fat metabolism
Glucose metabolism
Protein synthesis
Storage of vitamin, fat and iron

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3
Q

Haemoglobin die -> __-soluble ____ bilirubin -> liver -> __-soluble ____ bilirubin -> excreted in bile

A

Fat soluble unconjugated
Water soluble conjugated

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4
Q

Symptom related to bilirubin

A

Jaundice
Pruritus
Clay stool
Tea colored urines

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5
Q

Symptom related to albumin

A

Edema
Ascites
Increase abdominal girth
Weight gain

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6
Q

Symptom related to ammonia

A

Change of mental status
Sleep disturbances

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7
Q

Symptom related to blood clotting factors

A

Easy bruising
Melena

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8
Q

眼白

A

Sclera

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9
Q

palmar erythema

A

掌面紅斑

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10
Q

Spider angiomas

A

蜘蛛血管痣

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11
Q

Muscle atrophy

A

肌肉萎縮

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12
Q

skin excoriation

A

scratching

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13
Q

Asterixis

A

flap tremor

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14
Q

USG

A

Ultrasonography

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15
Q

What if patient allergic to contrast

A

Provide steriod cover

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16
Q

ERCP

A

Endoscopic retrograde cholangiopancreatography

17
Q

Type of liver cirrhosis

A

Alcoholic
Post-necrotic
Biliary

18
Q

Liver enlargement belongs to compensated or decompensated

A

Compensated

19
Q

Purpura

A

Decrease in platelet
紫斑症

20
Q

Normal liver size

A

6-12 in midclavicular line

21
Q

Main clinical manifestation of liver cirrhosis

A

Liver enlargement
Portal hypertension
Ascites
Varices
Jaundice
Coagulopathy
Spontaneous bacterial peritonitis
Edema
Vitamin deficiency and anemia
Pruritus
Hepatic encephalopathy

22
Q

Sign and symptoms of Ascites

A

Increase body weight
Increase abdominal girth
Increase SOB
Shifting if dullness during percussion

23
Q

Pharmacological management for Ascites

A

Loop diuretics (lasix)
IV albumin

24
Q

Management for Ascites

A

Paracentesis (abdominal tapping)

25
Q

Advise for Ascites and reason

A

Stay bed rest
To avoid activation of xxx system and sympathetic nervous systems

26
Q

Surgical intervention of ascite:
Shunt location and purpose

A

From portal vein to hepatic vein
To decrease the vascular resistance of liver

27
Q

S/s of jaundice

A

Yellowish discoloration of skin and sclera
Clay color stool
Tea color urine
Pruritus, fatigue, anorexia

28
Q

Types of jaundice
Causes

A

-Hepatocellular jaundice
Caused by liver failure
-Obstructive jaundice
Caused by obstruction flow of bile ducts

29
Q

Prolonged PT, INR

A

Coagulopathy
PT prothrombin time
INR clotting time

30
Q

Why spontaneous bacterial peritonitis

A

Infected by intestinal flora

31
Q

Formation of edema

A

Decrease albumin (plasma albumin concentration)
Failure to metabolize aldosterone -> increase sodium and water retention

Fluid shift from vascular system to peritoneal space

32
Q

Pathophysiology of hepatic encepthalopathy

A

Increase serum ammonia levels

33
Q

Why provide neomycin and lactulose
Route

A

Neomycin: to destroy bacteria in GI tract, reduce level of ammonia-forming bacteria in colon, reduce protein breakdown and production of ammonia

Lactulose: to expel the ammonia in feces, promote excretion of ammonia in stool

PO/PR

34
Q

Antidose for acetaminophen(paracetamol)
mushroom poisoning

A

N-acetylcysteine
Penicillin G and N-acetylcysteine

35
Q

Drug for nausea vomiting

A

Antiemetics

36
Q

Patient with liver disorder should avoid what drug

A

Aspirin
Sedative

37
Q

Nursing management: Diet

A

High calories, carbohydrates,
Low sodium(reduce edema), fat

Provide oral hygiene to increase appetite and reduce unpleasant smell

38
Q

Nursing management against Ascites

A

-Small and frequent meal to prevent fullness and bloating
-Elevate head of bed to reduce discomfort from abdominal distension

39
Q

Nursing management for pruritus

A

-Assess skin integrity
-Frequent turning to prevent pressure ulcer and skin breakdown
-soft clothes and bed lining to prevent skin scratching and infection from scratching
-provide tepid water bath, avoid alkaline soap or alcohol-based location