123: Neurotransmitters and cells of the nervous system Flashcards
support cells,
astrocytes
myelination
oligodendrocytes
macrophage like
microglia
make CSF and line the ventricles of the brain
ependymal cells
synthesise Glutamamte from GABA
glia
these receptors do not conduct ions and are coupled to intracellular signalling systems. the effects are therefore slow.
metabotrophic receptors
these receptors conduct ions and so directly affect membrane potential. They include glutamate, GABA, glycine, serotonin and acetylcholine
ionotrophic receptors
Activate GABAa receptors for…
sedation. block = hyper excitability/seizures
inhibitory neurotransmitter exclusive to brain and spinal cord
glycine.
neurotransmitter targeted by fluoxetine
serotonin (5-hydroxyteyptamine)
enterochromaffin cells secrete this neurotransmitter to stimulate peristalsis
serotonin
made by the basal forebrain, transmitter of neuromuscular junction and and lost in alzheimers
acetylcholine
made in the ventral midbrain. disordered in schizophrenia , parkinsons, tourettes and drug addiction.
dopamine
parkinsons treatments increase the abundance of this neurotransmitter
dopamine
made by the locus coeruleus
noradrenaline