12 - Asthma

Question 1

atopy

Answer 1

allergic rhinitis, eczema, asthma is classic triad
food allergies also common

basically just allergic prone phenotype

Question 2

relationship btwn aspirin allergy and asthma

Answer 2

pts w/ aspirin allergy often have intrinsic asthma and nasal polyps

Question 3

infectious triggers/inducers of asthma

Answer 3

childhood RSV
mycoplasma
chlamydia
viral URIs in general

Question 4

occupational substances that are linked to asthma

Answer 4

TDI (toluene di isocyanate)
TMI - tri metallic anhydride
organic dusts
animal/lab handlers, welders

Question 5

asthma is sometimes linked to what vasculitis

Answer 5

Churg Strauss

Question 6

what measurement indicates that asthma has worsened enough to require change in meds?

Answer 6

> 20% reduction in peak expiratory flow rate

Question 7

steps of asthma treatment

Answer 7

1 - SABA prn
2 - low dose ICS
3 - LABA
4 - inc ICS dose
5 - inc ICS dose
6 - oral corticosteroid

Question 8

why dont you use LABA as monotherapy in asthma?

Answer 8

tachyphylaxis

Question 9

SEs of beta agonists

Answer 9

tremor
tachycardia and arrhythmias
hypoxemia
hypokalemia