1.2 Flashcards
What kind of amino acids make proteins?
L amino acids
What is an L amino acid?
The amino group (NH3) comes before the carboxyl group (coo-)
What is the pKa of Lysine and Argentine?
10-12
What is the pKA of histidine?
6
What is the pKa of aspartic acid and glutamine?
3-4
What is a zwitterion? (Ampholyte)
A dipolar ion that acts as an acid or base
What does 2 zones of buffer mean in a titration curve?
The amino acid is not charged
What does 3 zones of buffer in a titration curve mean?
Look at middle pKa to see which amino acid it is
How are peptide bonds made?
Two amino acids join and water is lost to form the bond a
Phosphorylation
Adds a phosphate group to Ser, Thr, and Tyr
Enzyme activity
Sulfation
Only happens to Tyr
Hormones
Methylation
Adds methyl group to Lys or Arg
Are cysteine sulfhydryl groups oxidized or reduced?
Oxidized
What purpose do disulfide bridges serve?
Helps link amino acid chains together and helps with structure
Are the interior of beta barrels hydrophilic or hydrophobic
Hydrophobic