11.3 transduction Flashcards
transduction
usually a multistep pathway where a protein is activated y adding/releasing phosphate groups or releasing small ions and molecules to act as messengers
advantages for multiple steps
amplifying the signal
-more opportunities for coordination and regulation
how does it start
a signaling molecule binds to a receptor in the plasma membrane triggers the first step and then it activates another protein and so on until the protein for the final response is activated
an enzyme that transfers phosphate groups from ATP to a protein
protein kinase
Like tyrosine kinase dimer
A phosphorylation cascade
Series of proteins activate each other in turn by adding a phosphate group to the next in line
Protein phosphatases
Enzyme that remove phosphate groups from proteins
To inactivate protein kinases
Second messengers
Small no protein water soluble molecules or ions
First messenger
the signaling molecule that binds to the membrane receptor