11.2 reception Flashcards

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1
Q

the signaling molecule behaves like a

A

ligand

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2
Q

ligand

A

a molecules that specifically binds to another molecule

  • causes receptor protein to change in shape
  • or causes 2 receptor molecules to aggregate together
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3
Q

signal receptors in the plasma membrane are

A

water soluble and too large to pass through the plasma membrane

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4
Q

how do membrane proteins work

A

-water soluble signal binds to specific site in membrane

  • shape changes
  • or aggregates transmitting info (from the external environment)`
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5
Q

where are intracellular receptors

A

in the cytoplasm or nucleus in target cells

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6
Q

signal molecules for intracellular receptors

A
  • hydrophobic or small enough to pass through phospholipid bilayer in plasma membrane
  • steroids, thyroid hormones, nitric oxide (NO) -gas
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7
Q

3 major types of plasma membrane receptors

A

G protein coupled receptors
receptor tyrosine kinases
-ion channel receptors

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8
Q

3 common types of intracellular receptors

A

-steroids,
thyroid hormones,
nitric oxide (NO) -gas

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9
Q

how odes testosterone work

A
  • intracellular steroid is
  • secreted by testes-> blood -> cells
  • binds to receptor proteins
  • hormone/ protein complex changes shape and enters nucleus
  • controls male gender characteristics
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10
Q

what proteins control whether or not a gene is transcribed

A

transcription factors

  • testosterone was a transcription factor after it went into the nucleus
  • it turns on specific genes to be transcribed (by binding to them)
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11
Q

G protein coupled receptors

A

-plasma membrane receptor that works with a G protein to bind GTP (energy molecule)

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