112114 head and neck path Flashcards

1
Q

cold sores from what

A

HSV type I – herpes stomatitis

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2
Q

3 M’s for Tzank test for herpes stomatitis

A

multinucleation
molding
margination

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3
Q

squamout papilloma is associated with

A

low risk subtype HPV

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4
Q

precancerous lesions of oral cavity

A

leukoplakia

erythroplakia (usually associated with epithelial dysplasia)

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5
Q

sequence of development of squamous cell carcinoma

A

hyperplasia
dysplasia
carcinoma

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6
Q

epithelial dysplasia

A
proliferation of immature (basal) cells
loss of cell polarity
increased mitotic figures
variation in nuclear size and shape
hyperchromasia
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7
Q

squamous cell carconoma of oral cavity and larynx occurs usually what age?

A

50-70

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8
Q

squamous cell carcinoma of oral cavity and larynx occurs more often in males or females?

A

males

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9
Q

what risk factors are associated with sq cell carcinoma of oral cavity and larynx?

A

tobacco
alcohol
HPV high risk serotype infection

family hx
erythroplakia

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10
Q

histology of sq cell carcinoma

A

nests with keratin (pink) under basement membrane

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11
Q

nonkeratizing sq cell carcinoma-what is it associated with?

A

HPV high risk types

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12
Q

what are Schneiderian papillomas associated with

A

HPV low risk subtypes

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13
Q

what forms circles, rosettes?

A

olfactory neuroblastoma

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14
Q

what are risk factors for nasopharyngeal carcinoma?

A

geographic-Africa, China

EBV infection

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15
Q

most common salivary gland tumor

A

pleomorphic adenoma

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16
Q

pleomorphic adenoma

A

benign mixed tumor
pleomorphic
adenoma (proliferation of cells-epithelial and myoepithelial)

17
Q

Warthin tumor

A

microscopy: bilayered oncocytic (pink) epithelial cells and lymphocytes

18
Q

mucoepidermoid carcinoma

A

mixture of squamoid, mucous, and intermediate cells

19
Q

adenoid cystic carcinoma

A

microscopy:
perinerual invasion
CRIBRIFORM ARCHITECTURE (swiss cheese like)