112114 head and neck path Flashcards
cold sores from what
HSV type I – herpes stomatitis
3 M’s for Tzank test for herpes stomatitis
multinucleation
molding
margination
squamout papilloma is associated with
low risk subtype HPV
precancerous lesions of oral cavity
leukoplakia
erythroplakia (usually associated with epithelial dysplasia)
sequence of development of squamous cell carcinoma
hyperplasia
dysplasia
carcinoma
epithelial dysplasia
proliferation of immature (basal) cells loss of cell polarity increased mitotic figures variation in nuclear size and shape hyperchromasia
squamous cell carconoma of oral cavity and larynx occurs usually what age?
50-70
squamous cell carcinoma of oral cavity and larynx occurs more often in males or females?
males
what risk factors are associated with sq cell carcinoma of oral cavity and larynx?
tobacco
alcohol
HPV high risk serotype infection
family hx
erythroplakia
histology of sq cell carcinoma
nests with keratin (pink) under basement membrane
nonkeratizing sq cell carcinoma-what is it associated with?
HPV high risk types
what are Schneiderian papillomas associated with
HPV low risk subtypes
what forms circles, rosettes?
olfactory neuroblastoma
what are risk factors for nasopharyngeal carcinoma?
geographic-Africa, China
EBV infection
most common salivary gland tumor
pleomorphic adenoma