111214 intro to sleep Flashcards

1
Q

what kind of waves in different stages of sleep?

A

BATSDB mneumonic

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2
Q

in what stage is it low amplitude, high frequency EEG waveform?

A

awake and REM

in REM, there’s sawtooth waves

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3
Q

in what stage are there sleep spindles and K complexes?

A

stage 2

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4
Q

low frequency, high amplitude EEG characterizes which sleep stage?

A

3,4

delta waves

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5
Q

REM sleep usually changes how over the sleeping period?

A

REM episodes increase in length

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6
Q

sleep architecture of newborn compared to young adult?

A

cycle shorter, but total is longer. increased REM

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7
Q

sleep architecture of elderly compared to to young

A

little stage 4, 3. instead of 5 cycles, have 10-15 cycles

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8
Q

what type of sleep predominates the first half of the night

A

NREM

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9
Q

what kind of sleep predominates the last half of night

A

REM

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10
Q

stage 2 sleep accounts for about what percentage of the entire night?

A

45-55%

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11
Q

dreams are usually not recalled in what kind of sleep?

A

NREM

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12
Q

what sleep is associated with active dreaming?

A

REM

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13
Q

paradoxical sleep is another name for

A

REM sleep

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14
Q

sleep wake cycle is affected by what?

A

circadian factors

duration of wakefulness and sleep

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15
Q

process C

A

alerting signal that keeps you awake
at night, it shuts off

circadian oscillatory component affecting the propensity for sleep and waking

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16
Q

process H

A

sleep load
homeostatic process
the longer awake, the greater propensity to sleep

17
Q

what is responsible for circadian pattern?

A

neurons in suprachiasmatic nucleus of hypothalamus

18
Q

what does the internal biological clock match?

A

the day length by the environmental photoperiod

19
Q

how does resetting of biological clock occur?

A

mediated through photoreceptors in retina which send signals to SCN

20
Q

if you had eternal darkness, what would happen to sleep rhythm?

A

no cues–

so would sleep later and later each night

21
Q

process S

A

drive to sleep (increases with time in awake state)

22
Q

ascending projections from what affect the sleep wake cycle?

A

brainstem (serotnoinergic neurons in raphe pallidus,noradrenergic neurons in locus coeruleus)
and hypothalamus

23
Q

wakefulness is promoted by

A

increased excitatory and decreased inhibitory neuromodulators

circadian and homeostatic centers

24
Q

NREM sleep occurs when

A

when brainstem excitatory and hypothalamic circadian and homoestatic factors decrease

25
REM sleep occurs when?
when reduced NE and serotonin release inhibition of pontine PPT and LDT cholinergic neurons which activate REM system
26
REM sleep: discharge rate of neurons, cerebral glucose utilization, cerebral blood flow?
all increased
27
somatic activity in NREM vs REM sleep
NREM: few motor events, body repositioning REM: paralysis. phasic events (rapid eye movements, muscle twitches)
28
breathing during REM sleep
irregularities in timing and amplitude rib cage activity is reduced paradoxical respiration--rib cage moves inward when the abdomen moves outward
29
breathing patterns in NREM sleep
stage 1,2--not as regular stage 3,4--regular breathing
30
what decreases more during deep sleep: ventilation or metabolic rate?
ventilation, so PaCO2 increases | called sleep induced hypoventilation
31
decreased HR and CO during sleep are due to?
ANS--parasympathetic activity predominating in NREM and REM sleep
32
GH, parathyroid, cortisol levels in sleep?
GH: peak 90 minutes after sleep onset parathyroid: increased cortisol: cortisol decreases after beginning sleep. cortisol levels are lowest in early part of sleep and highest from 4-8am.
33
REM sleep--thermoregulation?
no regulation (no shivering response, no sweating at high ambient temps)
34
NREM sleep-thermoregulation?
lowered temperature set point