111214 intro to sleep Flashcards

1
Q

what kind of waves in different stages of sleep?

A

BATSDB mneumonic

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2
Q

in what stage is it low amplitude, high frequency EEG waveform?

A

awake and REM

in REM, there’s sawtooth waves

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3
Q

in what stage are there sleep spindles and K complexes?

A

stage 2

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4
Q

low frequency, high amplitude EEG characterizes which sleep stage?

A

3,4

delta waves

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5
Q

REM sleep usually changes how over the sleeping period?

A

REM episodes increase in length

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6
Q

sleep architecture of newborn compared to young adult?

A

cycle shorter, but total is longer. increased REM

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7
Q

sleep architecture of elderly compared to to young

A

little stage 4, 3. instead of 5 cycles, have 10-15 cycles

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8
Q

what type of sleep predominates the first half of the night

A

NREM

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9
Q

what kind of sleep predominates the last half of night

A

REM

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10
Q

stage 2 sleep accounts for about what percentage of the entire night?

A

45-55%

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11
Q

dreams are usually not recalled in what kind of sleep?

A

NREM

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12
Q

what sleep is associated with active dreaming?

A

REM

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13
Q

paradoxical sleep is another name for

A

REM sleep

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14
Q

sleep wake cycle is affected by what?

A

circadian factors

duration of wakefulness and sleep

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15
Q

process C

A

alerting signal that keeps you awake
at night, it shuts off

circadian oscillatory component affecting the propensity for sleep and waking

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16
Q

process H

A

sleep load
homeostatic process
the longer awake, the greater propensity to sleep

17
Q

what is responsible for circadian pattern?

A

neurons in suprachiasmatic nucleus of hypothalamus

18
Q

what does the internal biological clock match?

A

the day length by the environmental photoperiod

19
Q

how does resetting of biological clock occur?

A

mediated through photoreceptors in retina which send signals to SCN

20
Q

if you had eternal darkness, what would happen to sleep rhythm?

A

no cues–

so would sleep later and later each night

21
Q

process S

A

drive to sleep (increases with time in awake state)

22
Q

ascending projections from what affect the sleep wake cycle?

A

brainstem (serotnoinergic neurons in raphe pallidus,noradrenergic neurons in locus coeruleus)
and hypothalamus

23
Q

wakefulness is promoted by

A

increased excitatory and decreased inhibitory neuromodulators

circadian and homeostatic centers

24
Q

NREM sleep occurs when

A

when brainstem excitatory and hypothalamic circadian and homoestatic factors decrease

25
Q

REM sleep occurs when?

A

when reduced NE and serotonin release inhibition of pontine PPT and LDT cholinergic neurons which activate REM system

26
Q

REM sleep: discharge rate of neurons, cerebral glucose utilization, cerebral blood flow?

A

all increased

27
Q

somatic activity in NREM vs REM sleep

A

NREM: few motor events, body repositioning

REM: paralysis. phasic events (rapid eye movements, muscle twitches)

28
Q

breathing during REM sleep

A

irregularities in timing and amplitude
rib cage activity is reduced

paradoxical respiration–rib cage moves inward when the abdomen moves outward

29
Q

breathing patterns in NREM sleep

A

stage 1,2–not as regular

stage 3,4–regular breathing

30
Q

what decreases more during deep sleep: ventilation or metabolic rate?

A

ventilation, so PaCO2 increases

called sleep induced hypoventilation

31
Q

decreased HR and CO during sleep are due to?

A

ANS–parasympathetic activity predominating in NREM and REM sleep

32
Q

GH, parathyroid, cortisol levels in sleep?

A

GH: peak 90 minutes after sleep onset

parathyroid: increased
cortisol: cortisol decreases after beginning sleep. cortisol levels are lowest in early part of sleep and highest from 4-8am.

33
Q

REM sleep–thermoregulation?

A

no regulation (no shivering response, no sweating at high ambient temps)

34
Q

NREM sleep-thermoregulation?

A

lowered temperature set point