1.12 Enzymes Flashcards
Main idea
Enzymes are specific to their substrate and increase reaction rates by lowering activation energy
Define enzyme
An enzyme is a globular protein functioning as a biological catalyst.
Define active site
The site on the surface of an enzyme to which the substrate or substrates bind.
Explain substrate specificity
An enzyme has an active site that only fits with specific substrates.
Describe the induced fit model of enzyme substrate binding
The active site is not a rigid shape
its shape will change when the substrate binds to it
this makes the fit between the substrate and the enzyme very close
How do enzymes increase reaction rates
by lowering activation energy
reactions require an initial input of energy to proceed called activation energy
enzymes lower the required activation energy to allow faster reactions at lower temperatures
Enzymes lower required collision rate
all reactions either with or without enzymes need collisions between molecules to occur
many molecules have strong bonds holding them together so require powerful collisions at high speed to break these bonds
Enzymes allow optimum reaction rate at body temperature
Increasing the rate of collision to a rate at which these reactions would occur would require prohibitive amounts of energy, usually in the form of heat.
Enzymes stress substrate bonds so that a weaker collision is required to break them, reducing the amount of energy needed to cause these reactions to occur.