11. Introduction to Endocrinology – Hormones and Their Mechanisms of Action on Target Cells Only Flashcards
What signaling mechanism does thyroid stimulating hormone use?
cAMP (Adenylyl cyclase)
What signaling mechanism does glucagon use?
cAMP (Adenylyl cyclase)
What signaling mechanism does gonadotropin releasing hormone use?
IP3- Phospholipase C.
What signaling mechanism does oxytocin use?
IP3- Phospholipase C.
What hormones utilize the guanylyl cyclase signaling mechanism?
ANP.
NO.
What signaling mechanism does aldosterone use?
Steroid hormones.
What signaling mechanism does thyroxine releasing hormone use?
Phospholipase C.
What hormones utilize the phospholipase C signaling mechanism?
GnRH.
TRH.
Oxytocin.
What signaling mechanism does follicle stimulating hormone use?
Adenylyl cyclase.
What signaling mechanism does adrenocorticotropic hormone use?
Adenylyl cyclase.
What hormones utilize tyrosine kinases for their signaling mechanism?
Insulin.
Nerve growth factor.
Epidermal growth factor.
Was signaling mechanism does insulin use?
Tyrosine kinase.
What signaling mechanism does nitric oxide use?
Guanylyl cyclase.
What signaling mechanism do the thyroid hormones use?
Steroid hormones.
What hormones utilize the steroid hormone signaling mechanism via an intracellular receptor?
PET CAT on TV
Progesterone
Estrogen
Testosterone.
Cortisol (Glucocorticoids)
Aldosterone
Thyroid hormones (T3/T4)
Vitamin D
What signaling mechanism does atrial natriuretic peptide use?
cGMP-Guanylyl cyclase.
What signaling mechanism do IGF-1, insulin, and other growth factors use?
Tyrosine kinase- MAP kinase pathway
What 11 hormones utilize the adenylyl cyclase mechanism of action?
*FLAT ChAMP*
FSH
LH
ACTH
TSH
CRH
hCG
ADH (V2 rec)
MSH
PTH
Calcitonin
GHRH
What hormones use a nonreceptor tyrosine kinase?
PIG
Prolactin
Immunoglobulin
GH
via Jak/STAT pathway
