11. Introduction to Endocrinology – Hormones and Their Mechanisms of Action on Target Cells Only Flashcards

1
Q

What signaling mechanism does thyroid stimulating hormone use?

A

cAMP (Adenylyl cyclase)

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2
Q

What signaling mechanism does glucagon use?

A

cAMP (Adenylyl cyclase)

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3
Q

What signaling mechanism does gonadotropin releasing hormone use?

A

IP3- Phospholipase C.

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4
Q

What signaling mechanism does oxytocin use?

A

IP3- Phospholipase C.

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5
Q

What hormones utilize the guanylyl cyclase signaling mechanism?

A

ANP.

NO.

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6
Q

What signaling mechanism does aldosterone use?

A

Steroid hormones.

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7
Q

What signaling mechanism does thyroxine releasing hormone use?

A

Phospholipase C.

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8
Q

What hormones utilize the phospholipase C signaling mechanism?

A

GnRH.

TRH.

Oxytocin.

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9
Q

What signaling mechanism does follicle stimulating hormone use?

A

Adenylyl cyclase.

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10
Q

What signaling mechanism does adrenocorticotropic hormone use?

A

Adenylyl cyclase.

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11
Q

What hormones utilize tyrosine kinases for their signaling mechanism?

A

Insulin.

Nerve growth factor.

Epidermal growth factor.

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12
Q

Was signaling mechanism does insulin use?

A

Tyrosine kinase.

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13
Q

What signaling mechanism does nitric oxide use?

A

Guanylyl cyclase.

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14
Q

What signaling mechanism do the thyroid hormones use?

A

Steroid hormones.

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15
Q

What hormones utilize the steroid hormone signaling mechanism via an intracellular receptor?

A

PET CAT on TV

Progesterone

Estrogen

Testosterone.

Cortisol (Glucocorticoids)

Aldosterone

Thyroid hormones (T3/T4)

Vitamin D

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16
Q

What signaling mechanism does atrial natriuretic peptide use?

A

cGMP-Guanylyl cyclase.

17
Q

What signaling mechanism do IGF-1, insulin, and other growth factors use?

A

Tyrosine kinase- MAP kinase pathway

18
Q

What 11 hormones utilize the adenylyl cyclase mechanism of action?

A

*FLAT ChAMP*

FSH

LH

ACTH

TSH

CRH

hCG

ADH (V2 rec)

MSH

PTH

Calcitonin

GHRH

19
Q

What hormones use a nonreceptor tyrosine kinase?

A

PIG

Prolactin

Immunoglobulin

GH

via Jak/STAT pathway