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Immunosero Lab (Midterm) > 1.1 C Reactive Protein > Flashcards

1.1 C Reactive Protein Flashcards

1
Q

An Acute-phase reactant protein that usually rises in response to inflammation

a. C-Reaction protein
b. C-Reactive protein
c. C-Reactive enzyme
d. C-Relative protein

A

b

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2
Q

CRP is synthesized by what organ?

a. liver
b. spleen
c. pancreas
d. bone marrow

A

a

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3
Q

CRP is usually rise in?

a. Response to decreasing in leukocytes
b. Response to hyponatremia
c. Proliferation of Leukocytes
d. Inflammation

A

d

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4
Q

Levels of CRP rise and fall slowly with the onset and removal of the inflammatory stimulus, respectively

T or F?

A

F, Rise and fall “Rapidly”

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5
Q

CRP has both ________ and_______ properties

a. proinflammatory and preinflammatory
b. preinflammatory and anti-inflammatory
c. proinflammatory and anti-inflammatory
d. inflammation and interleukins

A

c

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6
Q

Properties of CRP that induce inflammation to the site by activating certain cells or humoral factor?

a. proinflammatory
b. preinflammatory
c. anti-inflammatory
d. interleukin

A

a

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7
Q

Properties of CRP that reduces or stop the inflammation in the site through assisting in killing pathogens

a. proinflammatory
b. preinflammatory
c. anti-inflammatory
d. interleukin

A

c

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8
Q

Sequence of production or the process of C reactive protein

  1. CRP helps in Opsonization, and activation
  2. Production of CRP by the liver
  3. infection or other pathology, activates innate immunity
  4. CRP is released in the circulatory system

a. 1,2,3,4
b. 3,4,2,1,
c. 3,2,4,1
d. 3,2,1,4

A

c

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9
Q

Opsonization is what properties of CRP?

a. proinflammatory
b. preinflammatory
c. anti-inflammatory
d. interleukin

A

c

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10
Q

Complement activation is part of what properties of CRP?

a. proinflammatory
b. preinflammatory
c. anti-inflammatory
d. interleukin

A

a

Complement activation indece inflammation

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11
Q

Complement activation is part of what properties of CRP?

a. proinflammatory
b. preinflammatory
c. anti-inflammatory
d. interleukin

A

a

Complement activation induce inflammation

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12
Q

Phagocyte activation is part of what properties of CRP?

a. proinflammatory
b. preinflammatory
c. anti-inflammatory
d. interleukin

A

a

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13
Q

CRP increases in which of the following?

  1. Parasitic infection
  2. Active rheumatic fever
  3. Rheumatoid arthritis
  4. Viral infections
  5. Tuberculosis

a. 1,4,5
b. 1,2,3,5
c. 1,2,3,4,5
d. 2,3,4,5

A

d

Bacterial infection causes CRP increases, not Parasitic infection

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14
Q

Which of the following increases CRP?

  1. Blood transfusion
  2. Surgery
  3. Burns
  4. pemphigus vulgaris
  5. bullous lesions

a. 3,4,5
b. 4,5
c. 1,2,3
d. 1,2,3,4
e. All of the above

A

e

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15
Q

Normal CRP level seen in healthy adults?

a. less than 0.3 mg/dL
b. more than 0.3 mg/dL
c. less than 3.0 mg/dL
d. more than 3.0 mg/dL

A

a

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16
Q

Normal CRP levels seen in minor elevation such as obesity, pregnancy, lifestyle or habits, etc.)

a. 0.3 - 0.5 mg/dL
b. 0.3 - 0.7 mg/dL
c. 0.3 - 1.0 mg/dL
d. 0.3 - 1.5 mg/dL

A

c

17
Q

What is the CRP levels for patients with Rheumatoid arthritis and SLE?

a. 0.3 - 1.0 mg/dL
b. 1.0 - 10.0 mg/dL
c. more than 10.0 mg/dL
d. more than 50.0 mg/dL

A

b (Moderate elavation)

18
Q

What is the CRP levels for patients with malignancies and myocardial infarction?

a. 0.3 - 1.0 mg/dL
b. 1.0 - 10.0 mg/dL
c. more than 10.0 mg/dL
d. more than 50.0 mg/dL

A

b (Moderate elevation )

19
Q

What is the CRP levels for patients with pancreatitis, bronchitis?

a. 0.3 - 1.0 mg/dL
b. 1.0 - 10.0 mg/dL
c. more than 10.0 mg/dL
d. more than 50.0 mg/dL

A

b (Moderate elevation)

20
Q

What is the CRP levels for patients with viral infections, systemic vasculitis, major trauma?

a. 0.3 - 1.0 mg/dL
b. 1.0 - 10.0 mg/dL
c. more than 10.0 mg/dL
d. more than 50.0 mg/dL

A

c (Marked elevation)

21
Q

What is the CRP levels for patients with Acute bacterial infections?

a. 0.3 - 1.0 mg/dL
b. 1.0 - 10.0 mg/dL
c. more than 10.0 mg/dL
d. more than 50.0 mg/dL

A

d (Severe elevation)

22
Q

What is the CRP levels for patients with Acute bacterial infections?

a. 0.3 - 1.0 mg/dL
b. 1.0 - 10.0 mg/dL
c. more than 10.0 mg/dL
d. more than 50.0 mg/dL

A

d (Severe elevation)

23
Q

Which of the following is true about the principle of CRP test?

  1. Latex particles coated with IgM antibodies specific to CRP
  2. Patient serum contains CRP antibodies
  3. Latex particles coated with CRP specific for CRP antibodies
  4. The principle of CRP test is related to reverse passive agglutination

a. 1,4
b. 2,3,
c. 1,2,3,
d. Only 4

A

d

(Latex particles coated with IgG antibodies specific to CRP, The patient serum contains CRP)

24
Q

What should be the expected result or positive result for CRP test?

a. Hemolysis
b. Precipitation
c. Agglutination

A

c

25
Q

What is the latex particle used in CRP test?

a. Polystyrene
b. Nylon
c. Polyester
d. Rubber

A

a

26
Q

Sample used in CRP test?

a. Fresh Serum
b. Fresh plasma
c. Fresh CSF
d. Fresh Urine

A

a

27
Q

Storage for specimen of CRP?

a. 2-8C for 24 hrs
b. -20 C for 48 hrs
c. 2-8C for 48 hrs
d. -20 C for 24 hrs

A

c

28
Q

Specimen for CRP can be hemolyzed and lipemic?

T or F?

A

F

29
Q

Detergent contamination may result as?

a. False positive
b. False negative
c. both

A

a

30
Q

Use of plasma rather than serum can lead to?

a. False positive
b. False negative
c. both

A

a

31
Q

The result of CRP should not be read beyond?

a. 1 min
b. 2 mins
c. 3 mins
d. 4 mins

A

b

32
Q

The result of CRP being read beyond 2 mins will result to?

a. False positive
b. False negative
c. Both

A

c

33
Q

Components in the CRP test procedure should at what temp?

a. Cold temp
b. Room temp
c. Freezing temp

A

b

34
Q

Why room temperature for CRP components?

a. To maintain IgG components
b. To maintain IgM components

A

a

35
Q

Color of Negative control for CRP

a. Red
b. Blue
c. White

A

b

36
Q

Color of Potive control for CRP

a. Red
b. Blue
c. White

A

a

37
Q

Color of CRP reagent

a. Red
b. Blue
c. White

A

c

38
Q

Sequence of procedure for CRP?

  1. 1 drop of latex reagent to each circle
  2. 40 uL of undiluted serum for patient sample circle
  3. 1 drop of NC and PC on each NC and PCcircle
  4. Spread each circle
  5. Place test card on automatic rotator for 2 mins
  6. check results

a. 1,4,3,2,5,6
b. 1,4,2,3,5,6
c. 1,2,3,4,5,6
d. 1,4,5,2,3,6

A

c

Immunosero Lab (Midterm) (5 decks)

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