11 Flashcards
The membrane is a natural barrier to _________ because ________.
Polar and charged molecules, the membrane’s interior contains nonpolar and hydrophobic fatty acid tails that do
not interact well with polar and charged molecules.
O2 and steroid hormones (such as testosterone) easily cross the membrane
because these molecules are _______ (chemical property). Since the core of the membrane is _______ (chemical property), the membrane does not repel these molecules.
Nonpolar
Glucose and Na+ cross the membrane poorly or not at all because these molecules are _______ (chemical property(ies)). Since the core of the membrane is _______ (chemical property), the membrane repels these molecules.
Polar, nonpolar
Membrane transport
Moving from an area of high concentration to low, a molecule is:
1. Moving _______ the concentration gradient
2. Uses _______ transport
With, passive
Membrane transport
Moving from an area of low concentration to high, a molecule is:
1. Moving _______ the concentration gradient
2. Uses _______ transport
3. The movement is energetically _______
Against, active, unfavorable
Membrane transport
To determine the type of transport that occurs, one needs to consider:
1.
2.
Concentration gradient (moving with or against the gradient), Chemical property of molecule (nonpolar vs polar or charged or large)
Transporter characteristics & Energetic coupling
1. _______: ATP is dephosphorylated and a
membrane protein is phosphorylated. This causes the membrane protein to change shape to allow for the movement of a molecule in an unfavorable direction.
How ATP is used in membrane transport
Transporter characteristics & Energetic coupling
2. _______: A transporter protein
must specifically bind to each of the molecules in one compartment, and
then the protein must change shape in order to release the molecules into
a different, specific compartment.
How the transport of molecules can be coupled
If provided a model of a membrane transport process, describe how you would
determine:
1. Whether passive or active transport is required:
i.
ii.
Pa,ssive transport if molecule movements are towards equilibrium (high to low), Active transport if molecule movements are away from equilibrium (low to high)
If provided a model of a membrane transport process, describe how you would
determine:
2. If passive transport, whether a protein is required:
i.
ii.
If the molecule is small and nonpolar, simple diffusion is used (no protein)
If the molecule is polar, charged, or large: facilitated diffusion through a carrier or channel is needed
If provided a model of a membrane transport process, describe how you would
determine:
3. If active transport, what is the energy source:
ATP or the favorable movement of another molecule through the same transporter protein