1002 Exams Flashcards
Which of the following is not required for transcription
1) DNA template.
2) RNA polymerase
3) RNA ligase
4) ribonucleosid triphosphates ( ATP,GTP I CTP I UTP)
5) magnesium ions
3
DNA is a double stranded molecule consists of 2 polynucleotide chains. Complemetary bases of nucleotides are bonded together via;
A)Phosphate bonds
B) Hydrogen bonds
C) Phospho diester bonds
D) Sulphate bonds
E) Covalent bonds
B
which of the followings are tandem DNA repeats in eukaryotic genome?
AJ Telomeric ONA
Dj latrons
D) SINE
C) Exons
E) Activators
A
Which of the following proteins are mutated in a disease syndrome that cause cillary immotality
Dynein
Affected patients produce antibodies against desmosomal cadherins that cause a skin disease called
A) Kartagener’s syndrome
B) Familial hypercholesterolemia
C) Pemphigus
D) Cardiomyopathy
E) Hereditary deafness
C
Which of the followings is true for nucleolus?
A)the site for DNA synthesis
B) the site for protein synthesis
C) the site for ribosome production
D) the site for mRNA processing
E) the site for mRNA synthesis
C
Which of the followings is coding DNA sequences in eukaryotic GENE structure?
Al Telomeres
B) Intron C) SINE D) Exon
E) Centromeric DNA
D
Apoptosis is characterised by all the followings
EXCEPT?
A) Cell shrinkage
B) Cleaveage of cellular proteins by activated caspases
CL. Cell swelling
D) internucieosomal chromatin degradation, nuclear fragmentation
E) Blebbing of the plasma membrane
C
37) Which of the followings is TRUE for splicing?
A) Removal of introns from pre mRNAs
B) Removal of Exons from pre mRNAS
C) Addition of tail region
D) Binding of transcription factors to the promoter
E) Unwinding of DNA
A
All of the followings is required for replication EXCEPT?
A) A single-stranded DNA template.
B) Primase
C) dNTPs (dATP, dTTP, dGTP, dCTP)
D) An RNA molecule called Primer
E) RNA polymerase
E
What is used to uptake of cholesterol (LDL) from extracellular environment? R
Receptor mediated endocytosis
Which of the following cell types contain euchromatic nucleus
Motor neurons
Excessive activation of mans results in uncontrolled division and tumor development.
A) Receptor Tyrosin Kinases
B) G protein coupied receptors
C) Ion channel linked receptors
D) Nuclear receptors
E) Notch-Delta
A)
Which of the following signalling molecules can not cross the cell membrane and
bind cell surface
receptors?
A) Estrogen
B) Peptide hormones
C NO
D) Vitamin D
E) None of the above
B
Which of the following proteins provide strong cell-cell attachment?
A) Connexin
B) Cadherin
C) Integrin
D) Claudin
E) Occludin
B
