1002 5th Pdf Flashcards
Cell death 8
Apoptosis
Necrosis
Apoptosis is important in
Embryonic development
Maintenance of tissue homeostasis
Eliminate unneeded or aging cells
DNA damage induces
Apoptosis
Apoptosis role in development
• by eliminating unwanted cells from a variety of tissues.i.e.
• 1-Elimination of larval tissues during amphibian metamorphosis
• Elimination of the tissue between the digits during the formation of fingers and toes
• During development of the nervous system 50% of developing neurons eliminated by apoptosis.
Characteristics of apoptosis
Shrinkage
Blabbing the plasma membrane
Chromatin condensation
Internuleosomal degradation
Nuclear fragmentation
Cell breaks into small
Phagocytosis
Genes of apoptosis
Ced-3 → cell death
Ced-4→ cell death
Ced -9→ cell survival